brain.mgz is denoised to create antsdn.brain.mgz. This volume is then used to create the initial surface. The final surfaces are created from the unfiltered brain.mgz but using the orig surface created with the denoised brain.mgz. So the denoising helps to create the orig surface which is then used to initialize the final surfaces.

On 8/25/2020 5:37 PM, Alexopoulos, Dimitrios wrote:

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I’m looking through the pipeline table , looking to see where the orig surfaces are created, which appear to be in autorecon2 /tessellation step . What advantage is gained by denoising the image (which image is actually denosed?) at this stage if id does not contribute the final surfaces?

Sorry for asking for more detail, just want to make sure I understand the application of the utility. Many groups are now denoising their input images into many pipelines.

Jim

*From:* freesurfer-boun...@nmr.mgh.harvard.edu <freesurfer-boun...@nmr.mgh.harvard.edu> *On Behalf Of *Douglas N. Greve
*Sent:* Tuesday, August 25, 2020 4:05 PM
*To:* freesurfer@nmr.mgh.harvard.edu
*Subject:* Re: [Freesurfer] use of ANTs Denoising in FS 7.1

** External Email - Caution **

It is only used to create the orig surface. It is not used in the volume segmentation or the final placement of the surfaces. Volume smoothing of any kind has the potential to bias the surface placement so we recommend against denoising the input.

On 8/25/2020 4:56 PM, Alexopoulos, Dimitrios wrote:

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    Hi all,

    In previous datasets, and prior to FS 7, we independently ran ANTs
    denosing on the input T1s prior to running recon-all,

    However, FS 7.1 now appears to use the  denosing utility in parts
    of the pipeline.

    “ANTS denoise is used when creating the orig surface (but not
    thefinal surfaces)”

    Does this mean the denoised image is only used in the segmentation
    part of the pipeline (to generated the aseg.mgz) and does not
    propagate through to final surfaces?  Why not use  denoised T1
    through the surface-generation phase of the pipeline.

    Can you provide some further clarification.


    Thx.

    Jim

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