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Hello Freesurfer Experts!

I met the  mri_glmfit error:  matrix is ill-conditioned or badly scaled, condno 
= 1e+08.I am trying to run a 8 group 3 variables analysis: with diagnosis being 
my
variable of interest and trying to regress out the effects of 
gender,background,age,education and seizure.  1. Command line:
      mris_preproc --fsgd qdec/group.fsgd --cache-in thickness.fwhm10.fsaverage 
--target fsaverage --hemi lh --out lh.thickness.fwhm10.groups.mgh

       mri_glmfit --y lh.thickness.fwhm10.groups.mgh --fsgd group.fsgd dods --C 
Difference.group.mtx --surf fsaverage lh --cortex --glmdir 
fwhm10.thickness.glmdir 

  2. The FSGD file (see attached)
  3. And the design matrix:
     1 1 1 1 -1 -1 -1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0    (or 
see attached)

I encounter this error. I have no idea how to proceed.Is all this because I 
have too many covariates?
I am looking forward to your response!
Thanks,


Kan






 

Attachment: Difference.group.mtx
Description: Binary data

Attachment: group.fsgd
Description: Binary data

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