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I met the mri_glmfit error: matrix is ill-conditioned or badly scaled, condno = 1e+08.I am trying to run a 8 group 3 variables analysis: with diagnosis being my variable of interest and trying to regress out the effects of gender,background,age,education and seizure. 1. Command line: mris_preproc --fsgd qdec/group.fsgd --cache-in thickness.fwhm10.fsaverage --target fsaverage --hemi lh --out lh.thickness.fwhm10.groups.mgh mri_glmfit --y lh.thickness.fwhm10.groups.mgh --fsgd group.fsgd dods --C Difference.group.mtx --surf fsaverage lh --cortex --glmdir fwhm10.thickness.glmdir 2. The FSGD file (see attached) 3. And the design matrix: 1 1 1 1 -1 -1 -1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 (or see attached) I encounter this error. I have no idea how to proceed.Is all this because I have too many covariates? I am looking forward to your response! Thanks, Kan
Difference.group.mtx
Description: Binary data
group.fsgd
Description: Binary data
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