Hi Markus - If you were to find longitudinal changes in this study, you would
have no way of knowing if they are changes in the brain or changes in the
instrument used to measure the brain.
a.y
________________________________
From: freesurfer-boun...@nmr.mgh.harvard.edu
<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Markus Gschwind
<markus.gschw...@gmail.com>
Sent: Friday, January 31, 2020 6:04 PM
To: freesurfer <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] Question longitudinal study about treatment effect with
change of scanner and head coil?
External Email - Use Caution
Dear experts,
I am reviewing a study that proposes a longitudinal study in patients across
several years on the effect of medical treatment in terms of fcMRI and
DTI-connectivity measures.
However, in several but not all patients, the scanner was upgraded from Trio to
Prisma and the head coil was changed from a 12 to a 20-channel. Every patient
had the upgrade at another time point.
I would like to hear your opinion on this. In my experience, the scanner
upgrade and especially the head coil upgrade heavily affected the images.
So I have fundamental doubts about the feasibility. What would be the
conditions under which it could be acceptable?
Thank you in advance!
Best, Markus
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