[Freesurfer] Thickness problem

[Gwang-Won Kim]

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Hi there,

 

I obtained results for right thickness using aparcstats2table.

Then, ANCOVA was used to compared right thickness between two group (age, sex, edu, ICV as covariates)using SPSS.

A group showed higher right thickness in the superior frontal gyrus compared with B group (p=0.001).

 

To see voxel-wise map in same data, I tried to process "mris_preporc", "mri_surf2surf", and "mri_glmfit"

But the group showed higher right thickness in the middle frontal gyrus compared with B group (p<0.005).

I don't understand why data is different.

In ROI analysis, the group showed higher right thickness in the superior frontal gyrus compared with B group, but  the group showed higher right thickness in the middle frontal gyrus compared with B group in the voxel-wise map (p<0.005).

Please recommend me about it. 

 

mris_preproc --fsgd g1v4.fsgd --target fsaverage --hemi rh --meas thickness --out rh.g1v4.thickness.00.mgh

 

mri_surf2surf --hemi rh --s fsaverage --sval rh.g1v4.thickness.00.mgh --fwhm 10 --cortex --tval rh.g1v4.thickness.10B.mgh

 

itmri_glmfit --y lh.g1v4.thickness.10B.mgh --fsgd g1v4.fsgd --C group.diff.mtx --surf fsaverage rh --cortex --glmdir rh.g1v4.glmdir

 

 

g1g4.fsgd (subjects 50)

Class Group1

Class Group2

Variables age sex edu ICV

Input eewe Group1 34 1 13 1753213

Input ffds Group2 32 1 13 1753213

Input erfg Group2 33 1 13 1753213

Input gdds Group1 31 2 12 1753213

 

 

group.diff.mtx

1 -1 0 0 0 0 0 0 0 0

 

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