depends on what you want in the end. You can do that analysis, but 
p-values will be meaningless. Do you just want the difference between 
the subject and the group mean? If so, that will work. It should also 
give you z-values if that is of intereest

On 7/18/19 2:33 PM, m s wrote:
>
>         External Email - Use Caution
>
> Hello Freesurfer experts!
> I need to compare one patient to a group of controls and I wanted to 
> know which is the best way to do this.
> Is it correct to do it with group analysis when 1 group only has one 
> patient, thus no stdev, and the other group (controls) has for ex 20 
> patients?
> Is there a better choice for this situation or a prefered way to 
> visualize result in this case??
> Thank you!
> Mercedes
>
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