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Hi Douglas,

In order to apply intensity normalization to non-PVC PET images based on mean 
intensity from reference region in gtmseg.mgz, is it better to realign & 
reslice PET image onto gtmseg space or the reverse way ? How is it done when 
dealing with PVC images using gtmpvc command ?

I would like to avoid too many reslicing operations before volume to surface 
projection, how would you deal with it ?

Best,
Matthieu

> Le 28 janv. 2019 à 17:41, Greve, Douglas N.,Ph.D. <dgr...@mgh.harvard.edu> a 
> écrit :
> 
> If you intend to use one of the aseg structures, then they are the same. 
> 
> On 1/28/19 10:14 AM, Matthieu Vanhoutte wrote:
>>         External Email - Use Caution        
>> 
>> Hi Douglas,
>> 
>> 
>>> Le 25 janv. 2019 à 18:01, Greve, Douglas N.,Ph.D. <dgr...@mgh.harvard.edu 
>>> <mailto:dgr...@mgh.harvard.edu>> a écrit :
>>> 
>>> 
>>> 
>>> On 1/25/19 7:57 AM, Matthieu Vanhoutte wrote:
>>>>         External Email - Use Caution        
>>>> 
>>>> Dear Douglas,
>>>> 
>>>> Could you precise me:
>>>> 1) Is the intensity rescaling of PET image included in the mri_gtmpvc 
>>>> command based on reference region in gtmseg.mgz file rather than aseg.mgz ?
>>> It depends. If you are using pons, then that is not part of the aseg and is 
>>> generated as part of the creation of gtmseg. But most of the rest of gtmseg 
>>> is derived from the aseg and surfaces.
>> 
>> Is it better to use gtmseg.mgz or aseg.mgz to extract reference region’s 
>> mean intensity ?
>> 
>> 
>>>> 2) Is this rescaling applied before PVE correction or after (i.e. based on 
>>>> PVE corrected reference region’s mean intensity) ?
>>> After
>>>> 
>>>> Many thanks in advance for helping.
>>>> 
>>>> Best,
>>>> Matthieu
>>>> 
>>>>> Le 7 janv. 2019 à 17:26, Greve, Douglas N.,Ph.D. <dgr...@mgh.harvard.edu 
>>>>> <mailto:dgr...@mgh.harvard.edu>> a écrit :
>>>>> 
>>>>> 
>>>>> 
>>>>> On 1/7/19 11:18 AM, Matthieu Vanhoutte wrote:
>>>>>>         External Email - Use Caution        
>>>>>> 
>>>>>> 
>>>>>> I used the following command to obtain only rescaled voxel-wise PET 
>>>>>> image (with no PVC):
>>>>>> mri_gtmpvc --i PET.nii.gz --reg Pet2T1.register.dof6.lta --psf 0 
>>>>>> --no-tfe --seg gtmseg.mgz --default-seg-merge --auto-mask PSF .01 --rbv 
>>>>>> --o  nopvc
>>>>>> 
>>>>>> If I omitted --rbv or --mgx option I didn't get the rescaled voxel-wise 
>>>>>> PET image (without PVC). Could I obtain the rescaled voxel-wise PET 
>>>>>> image (without PVC) just by dividing each voxel of the native PET image 
>>>>>> by the mean of the reference region ?
>>>>> Yes
>>>>>> 
>>>>>> Best,
>>>>>> Matt
>>>>>> 
>>>>>> Le lun. 7 janv. 2019 à 16:01, Greve, Douglas N.,Ph.D. 
>>>>>> <dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu>> a écrit :
>>>>>> I'm not sure what you mean. If you are turning off PVC, why are you 
>>>>>> computing RBV and MGX? What is your command line? What do you mean that 
>>>>>> these options don't seem to work?
>>>>>> 
>>>>>> On 12/21/18 2:22 PM, Matthieu Vanhoutte wrote:
>>>>>>>         External Email - Use Caution        
>>>>>>> 
>>>>>>> Hi Douglas,
>>>>>>> 
>>>>>>> Thanks for helping.
>>>>>>> 
>>>>>>> To have an only rescaled voxel-wise PET image, these options seem to 
>>>>>>> work only when -rbv method is used and not -mgx.
>>>>>>> 
>>>>>>> Do you know why ?
>>>>>>> 
>>>>>>> Best,
>>>>>>> Matthieu 
>>>>>>> 
>>>>>>> 
>>>>>>> Le mar. 18 déc. 2018 à 17:58, Greve, Douglas N.,Ph.D. 
>>>>>>> <dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu>> a écrit :
>>>>>>> You will need to set --psf 0 and --no-tfe to fully turn off PVC. 
>>>>>>> 
>>>>>>> On 12/18/18 4:50 AM, Matthieu Vanhoutte wrote:
>>>>>>>>         External Email - Use Caution        
>>>>>>>> 
>>>>>>>> Hi Douglas,
>>>>>>>> 
>>>>>>>> Could you help me on this point ?
>>>>>>>> 
>>>>>>>> Best,
>>>>>>>> Matthieu
>>>>>>>> 
>>>>>>>> 
>>>>>>>> Le mer. 12 déc. 2018 à 10:50, Matthieu Vanhoutte 
>>>>>>>> <matthieuvanhou...@gmail.com <mailto:matthieuvanhou...@gmail.com>> a 
>>>>>>>> écrit :
>>>>>>>> Dear Douglas,
>>>>>>>> 
>>>>>>>> Is it possible to use mri_gtmpvc command in order to intensity 
>>>>>>>> normalize PET images without applying PVE correction by setting --psf 
>>>>>>>> to 0 ?
>>>>>>>> 
>>>>>>>> Best,
>>>>>>>> Matthieu
>>>>>>>> 
>>>>>>>> 
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