Hi Xiaoyu, 

please keep the previous conversation as inline citation below so I know what 
we discussed before. 

What I mean is to process every subject only once and not twice (with flipped 
images, if that is what you did?). 

Then run xhemi analysis on the subject-level. Invert the sign of the left-right 
difference depending on which is the diseased hemi. Then do a regular analysis 
on that. Nothing paired. 

Best, Martin



> On 30. Aug 2018, at 18:29, Wang, Xiaoyu <xwan...@pennstatehealth.psu.edu> 
> wrote:
> 
> 
> 
> 
> Thanks Martin,
>  
> Yes, I did mean to have the right hemisphere added to the left hemisphere as 
> a new time point.
>  
> Can you explain on what you mean by run every subject only once?
> Do you mean to run xhemi for all of the subjects and then run a paired 
> analysis?
>  
> Xiaoyu
>  
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