I don't think it is correct conceptually. By including SNR as a
covariate, you are saying that you expect the thickness to increase with
higher SNR and decrease with lower SNR. This does not make sense to me.
It sounds like you are trying to do a mixed effects analysis where you
weight by the SNR. Still, mathematically, this is not a true mixed
effect analysis (which requires estimates of the within and between
subject noise). `
On 8/3/18 10:57 AM, John Anderson wrote:
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Daer FS experts,
I would like to inquire about including SNR as a covariate for the
between groups cpmparison in cortical thickness. Is this procedure
correct mathematically? Do I need to demean the SNA values before
including it covariates? Finally, do you recommend any quality
parameters other than SNR to be included covariate?
I look forward to learn from your expertise,
Thanks,
John
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