Hi Guillaume

I certainly wouldn't trust the thickness values anywhere near the lesion. What exactly are you trying to compute?

cheers
Bruce
On Thu, 31 May 2018, Guillaume Bellanger wrote:


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Hi Freesurfers users,

I am looking on cortical thickness after ischemic stroke, especially stroke 
with cortical
involvment. Freesurfer is validated in this population, Li, Q. (2015).

When I check the surfaces on Freeview, cortical infarcts are excluded (which is 
great because of the
major anatomy distorsion) but the pial and white surfaces (in contact to the 
area excluded) are
different from zero. It seems that Free-surfer still calculates the cortical 
thickness as an average
measure of the surfaces in contact to the area excluded (which doesn't have any 
grey matter !). I
send you a picture to illustrate my question.

I am wondering: how does Freesurfer calculate the surfaces in contact to a 
cortical area excluded ?
If the areas are excluded does it have any consequences on the GLM with QDEC ?

Thanks a lot

Guillaume


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