What is funcVol? An individual functional? If so, then use --12 (12 dof 
to account for scaling). In general, we don't recommend doing cross 
subject registration with BBR as it is really not appropriate for that 
kind of thing.


On 05/03/2018 01:30 PM, David Beeler wrote:
>
>
> Hi,
>
> I'm trying to register and transform some raw functional data 
> (108x108x72x175, 2mm iso voxels) to MNI space, while keeping the low 
> res dimensions.
>
> I have tried:
> bbregister --s MNI152_FS --mov funcVol --reg func2mni.lta --init-fsl 
> --bold
> mri_vol2vol --mov funcVol --reg func2mni.lta --o funcVolMNI --fstarg 
> --no-resample --nearest
> mri_vol2vol --mov funcVol --reg func2mni.lta --o funcVolMNI --fstarg 
> --no-resample
>
> And this looks pretty good, but not perfect... the functional data is 
> oriented correctly but the brain seems to be a centimeter or two 
> smaller in multiple dimensions, see:
>
> http://web.mit.edu/dsbeeler/www/images/bbregister-mni.png
>
> I'm not too surprised since the MNI brain is blurry and oddly round, 
> but presumably there is a way to do this transformation more 
> accurately. I've run mri_cvs_register for this subject using the --mni 
> flag:
>
> mri_cvs_register --openmp 8 --mni --mov $subjID --outdir $mniDir
>
> And for other applications I use this m3z file to transform volumes 
> between MNI orig.mgz and individual subject orig.mgz, but is there a 
> way to use it to transform functional data to MNI space while keeping 
> the functional dimensions?
>
> I could do:
>
> mri_vol2vol --mov funcVol --targ $SUBJECTS_DIR/$subjID/mri/orig.mgz 
> --reg register.dof6.lta --nearest --o template-in-anat.nii.gz
>
> mri_vol2vol --noDefM3zPath --targ $SUBJECTS_DIR/$subjID/mri/orig.mgz 
> --mov template-in-anat.nii.gz --m3z 
> $mniDir/final_CVSmorph_tocvs_avg35_inMNI152.m3z --o 
> template-in-MNI-m3z.nii.gz --nearest
>
> But not only is this unideal because it requires upsampling the 
> functional data to 256x256x256, it also gets these funky wavy distortions:
>
> http://web.mit.edu/dsbeeler/www/images/m3z-mni.png
>
>
> Any thoughts are appreciated, thanks!
>
> -DB
>
>
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