Dear FreeSurfer experts,

We want to implement a deface method to ensure anonymity of participants before 
making the data available to researchers. Because the raw data is stored on the 
imaging platform XNAT, we preferred the mask_face method implemented on the 
XNAT server rather than FreeSurfer’s defacing. However, we will be using 
FreeSurfer for processing and segmentations afterwards. I am currently 
investigating the effect of face and earmasks on brain measures. I used 
FreeSurfer v5.3 (freesurfer-x86_64-unknown-linux-gnu-stable5-20130513) and the 
mask_face function developed for XNAT (Milchienko & Marcus, 2013) with the 
default normalized filter. The masks were not invasive and did not overlap with 
brain tissue.

I compared output of the recon-all between T1 scans with and without masked 
face for a small sample. I found high correlations between the output of the 
two scans (extracted values: cortical thickness, surface area, (sub)cortical 
volume, global values). Slight differences seem to occur from the start of the 
recon-all (talairach transform). Adding ear masks to the face-masked scans, 
made the differences smaller (i.e. higher correlations with raw scans). Also, 
the recon-all run time appears to be reduced.

Could you explain how face and ear information is used in the recon-all and why 
adding ear masks to masked-face scans might reduce run-time and improve 
reliability? Could it be the case that skull stripping is easier without ears 
for example?
Thank you in advance.

Kind regards,
Elizabeth

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Elizabeth Buimer, Research Assistant
Department of Psychiatry, UMC Utrecht
Room: A.01.161
e.e.l.bui...@umcutrecht.nl



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