Hi Tamara

have you visualized the multiple time points of a subject whose ventricular 
volume is decreasing? How big a decrease are you seeing?

cheers
Bruce


On Tue, 5 
Sep 2017, Tamara Tavares wrote:

> Hello,
> I used the default longitudinal stream to calculate ventricular volumes over 
> time. When I examined
> the difference score (longitudinal-baseline) I noticed that for some 
> participants ventricular
> volumes decreased. The same site, scanner and scanning protocol was used for 
> both baseline and
> longitudinal scans. I processed the cross, template and longitudinal time 
> points on the same
> computer using the same Freesurfer version (v 5.1). Furthermore, this 
> decrease in ventricular volume
> is evident before and after manual corrects were made to the aseg file. Is it 
> common to see an
> decrease in ventricular volume over time? Can this be due to Freesurfer 
> variability or slight
> differences in the scanner over the two time points?
> 
> Thank you in advance for your help.
> 
> Best,
> Tamara
> 
>
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