that looks right. how different are the values?

On 04/05/2017 10:58 AM, Gullickson, James wrote:
> Hello all,
>
> I want to calculate a Ventricle-to-Brain ratio (VBR) as a measure of 
> parenchymal atrophy using Freesurfer version 5.3.0. I have tried to go 
> about this using the aseg.stats output (using asegstats2table), but am 
> running into inconsistencies.
>
> The basic calculation for VBR is:
>
> (Total Ventricular Volume/Total Brain Volume) * 100
>
> i.e. Bigler, E. D. (2013). Traumatic brain injury, neuroimaging, and 
> neurodegeneration. /Frontiers in human neuroscience/, /7/, 395.
>
>
> What is the best way to get Total Ventricular Volume (TVV) and Total 
> Brain Volume (TBV) for this calculation? I have tried several ways, 
> which lead to different values:
>
> TVV = left lateral ventricle + left inf lateral ventricle + right 
> lateral ventricle + right inf lateral ventricle + 3rd ventricle + 4th 
> ventricle + 5th ventricle + choroid plexus
>
> which gives me a different result than
>
> TVV = BrainSegVol - BrainSegVolNotVent
>
>
> and for TBV
>
> TBV = TotalGrayVol + CorticalWhiteMatterVol
>
> which differs from
>
> TBV = BrainSegVolNotVent
>
>
> Thank you for your help,
>
> James Gullickson
>
>
>
>
>
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