And to add to this. 

In a longitudinal study you search for small longitudinal changes. There you 
should never switch versions or OS across time points, period.
(Also in a cross sectional study you should never do it, but often the effect 
there, e.g. group differences, are much larger than processing bias. Still you 
never know. It all depends on the size of you effects.). 

Best, Martin


> On Nov 11, 2016, at 6:03 PM, anonymous anonymous <phoolandevi1...@gmail.com> 
> wrote:
> 
> Hi 
> 
> I am using recon-all in some longitudinal data on a ubuntu 16.04, and using 
> the development version of freesurfer as I was told here, because the other 
> current version doesnt work on ubuntu 16.04.
> 
> The problem is that the first scans were probablly processed using virtualbox 
> in a windows and an older version of freesurfer. 
> 
> 
> i think I already know the answer, that I can't do this if I dont want to 
> bias my results. Can I?
> 
> But I'm using a better computer now and I use the one with windows for other 
> analyses, so I wanted to know if I could install Virtual box on my ubuntu 
> 16.04 computer, and install the same version of linux used to process the 
> first measure. Should I also need to use the same version of freesurfer?
> 
> f the computer's specs are dfferent, does it matter? And if I assign 
> different cpu and ram on my virtual machine? 
> 
> Thank you!
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> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
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