Hi Doug,
I am sorry for sending multiple emails. I wanted to be sure that I understand 
it properly. Kindly:
My question is regarding "projfrac = -1" and "projfrc=-2" are the pointers in 
the figure located correctly where the analysis will be carried out?

Thanks again




-----Original Message-----
From: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Douglas N Greve
Sent: Friday, November 4, 2016 12:09 PM
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] mris_preproc

Do you have a question about the image?


On 11/04/2016 11:09 AM, Alshikho, Mohamad J. wrote:
> Thank you Doug!
> Kindly in the attached figure are the "projfrac" values for #4 and #5 correct 
> for at which level the analysis will be carried out.
>
> -----Original Message-----
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Douglas N 
> Greve
> Sent: Friday, November 4, 2016 10:29 AM
> To: freesurfer@nmr.mgh.harvard.edu
> Subject: Re: [Freesurfer] mris_preproc
>
>
>
> On 11/04/2016 07:25 AM, Alshikho, Mohamad J. wrote:
>>   Dear FS experts,
>>
>>   I ran surface based analysis using PET maps, and the pipeline 
>> reported, in FS list, by multiple colleagues as  the following:
>>
>> ·spmregister --s subj --mov pet.nii --reg reg.dat --out pet_t1.mgh
>>
>> ·mris_preproc --target fsaverage --hemi lh --iv subj1/ubject1_pet.nii 
>> subject1/pet/pet_2_T1_register.dat ..... --projfrac 0.5 --out lh.mgh
>>
>> ·mri_surf2surf --hemi lh --s fsaverage --fwhm 6 --cortex --sval 
>> lh.mgh --tval lh.sm6.mgh
>>
>> ·mri_glmfit--y lh.sm6.mgh--fsgd fsgd.txt--C 2gc0.mtx --surf fsaverage 
>> lh --cortex --glmdir lh.glmdir//
>>
>> ·then mri_glmfit-sim to correct for multiple comparison.
>>
>> I wanted to know the correct usage of the flag "*_projfrac_*" in the 
>> command "*_mris_preproc_*":
>>
>> My understanding is that this flag control running the surface based 
>> analysis far from the surface (i.e. close to the surface or deep in 
>> the white matter)
>>
>> ·If it is 0.5 èthat means the surface based analysis is running in 
>> the middle area between white and pial
>>
>> ·if it is zero èthe surface based analysis is running close to white 
>> matter
>>
>> ·if it is +1 èthat means the surface based analysis is running close 
>> to the pial
>>
>> ·if it is -1 èthat means the surface based analysis is running deep 
>> in the white matter
>>
>> Kindly:
>>
>> 1.Is this correct?
>>
> Yes
>> 2.Can I  use values like -2 or -3 ... etc to run the analysis deep in 
>> the white matter. I aim to run surface based analysis on multiple 
>> layers of the brain deep from the pial to investigate how the PET 
>> signal is going to change between these layers?
>>
> In principle, yes, but often what happens is that when you follow the normal 
> vector into the white matter that far, you end up in GM or CSF and not WM.
>> 3.What is the difference between the flag "*_projfrac_*" and the flag 
>> "*_projdis_*"
>>
> projdist will project an absolute distance (in mm). projfrac will 
> project a fraction of the thickness (as you describe above)
>> 4.If I replace the PET maps in the previous pipeline by diffusion 
>> maps? Is it keep valid for diffusion data?
>>
> I guess it depends on what you mean by "valid". As I mention above, it 
> will not necessarily sample WM, and that probably invalidates it 
> somewhat
>> Many Thank!
>>
>> Mohamad
>>
>>
>>
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> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> Outgoing: 
> ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>
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--
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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