One is a map-based/voxel-wise analysis, each voxel is treated 
separately. The aparc stats table is an average over all vertices in the 
ROI. If you have an effect that does goes across the ROI boundary, it 
could be lost in the ROI analysis. On the other hand, the ROI analysis 
may be more powerful because of the averaging across space and fewer 
issues with registration across subject


On 08/23/2016 04:59 PM, miracoo...@gmail.com wrote:
> Hello freesurfer experts,
> What's the difference between GLM surface based cortical thickness 
> analysis and the cortical thickness analysis performed when using 
> regions extracted from aparcstat table?
> Best,
> Paul
>
> Sent from my BlackBerry 10 smartphone.
>
>
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MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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