How do you know that the structural is left-right reversed? Or that the 
fMRI is? How did you create the nifti files?


On 08/16/2016 01:41 PM, Afzal, Afsana wrote:
> Hi,
>
> I'm having trouble co-registering a bunch of subjects whose T1 is 
> left-right reversed. While the orientation of the structural file in 
> the NIfTI header is LIA and the orientation of the functional volume 
> is LAS, visual inspection shows that the structural is left-right 
> reversed. I then followed the steps outlined in 
> https://surfer.nmr.mgh.harvard.edu/fswiki/LeftRightReversal 
> <https://surfer.nmr.mgh.harvard.edu/fswiki/LeftRightReversal> to rerun 
> the reconstruction and re-registered the subject but the registration 
> mincost value is still hovering around 0.9 even with the left-right 
> reversed structural.
>
> I've tried running registration with SPM and FSL; neither method is 
> able to register these subjects properly.
>
> With --init-fsl I get the following:
> WARNING: initial G-W contrast is negative, but expecting positive.
> If the mov data has a T1 contrast, re-run with --T1
>
> and with --init-spm I get:
> WARNING: bad orientation matrix (determinant = 0) in nifti1 file ...
>  ... continuing.
>
> At this point I'm out of ideas to try out. This issue is occurring for 
> over 170 subjects (data collected outside Martinos using non-siemens 
> scanners).
>
> Any help would be much appreciated!
>
> Thanks,
>
> Afsana
>
>
>
> ______________________________
> *Afsana Afzal*
> Clinical Research Coordinator
> Massachusetts General Hospital
> Division of Neurotherapeutics
> Department of Psychiatry: Neurosciences
> 149 13th St, Room 2612
> Charlestown, MA 02129
> Phone: 617-643-5129
> Fax: 617-726-4078
>
>
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