Hi Bruce,

> You can't just change which peak is the WM - lots of things downstream would 
> fail

That is unfortunate.

I've send you the subject files and the raw files via filedrop (per
these instructions
https://surfer.nmr.mgh.harvard.edu/fswiki/FtpFileExchange)


On Fri, Jul 29, 2016 at 4:38 PM, Bruce Fischl
<fis...@nmr.mgh.harvard.edu> wrote:
> Hi Tom
>
> it's tough for us to tell without some images or the data. If you upload the
> entire subject dir of a subject that failed we will take a look. You can't
> just change which peak is the WM - lots of things downstream would fail
>
> cheers
> Bruce
>
>
>
> On Fri, 29 Jul 2016, tvg[fs] wrote:
>
>> Dear community and developers,
>>
>> I am experiencing issues during the normalization step, converting
>> NU.mgz to T1.mgz. Gray matter is falsely recognized as white matter
>> and high intensity WM is ignored. The resulting T1.mgz collapses the
>> wrong voxels into the 110 bin.
>>
>> It seems that what mri_normalize assumes a peak in the WM intensity
>> distribution that is too low.
>> In NU.mgz WM seems centered around 140 not 110. Note that this is not
>> due to RF-field inhomogeneities. It is likely of physiological origin
>>
>> - Is there a way to explicitly tell mri_normalize to use a different
>> intensity peak?
>>
>> I realize that correction can be done with control points, however I
>> understand that does not compute a new intensity distribution, but
>> merely adds voxels around CPs. This is undesirable since I have >20
>> scans to process. Also this will not correct the falsely tagged GM
>> voxels.
>>
>> I've tried to trick mri_normalize by adjusting NU.mgz intensity by -30
>> (140-30 = 110). This did not give me the wished-for effect.
>> - Is it possible to bypass preprocessing steps of mri_normalize before
>> collapsing?
>>
>> - In general it would help if there is some elaboration on the options:
>> -no1d,
>> -nosnr,
>> -gentle,
>> -f vs -fonly,
>> -prune,
>> -g,
>> -monkey
>> - is [-monkey] just shorthand for [-no1d -n 1]?
>>
>> Thanks,
>> Tom
>>
>> System:
>> Mac OS X 10.10.5
>> freesurfer-Darwin-lion-stable-pub-v5.3.0
>>>
>>> mri_normalize --version
>>
>> stable5
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>>
>
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