It's surface-based analysis.

On Fri, Jul 22, 2016 at 1:43 PM, Douglas N Greve <gr...@nmr.mgh.harvard.edu>
wrote:

> Are you doing volume or surface-based analysis? If volume, then you'll
> need a volume mask and the --label is not appropriate.
>
> On 07/22/2016 01:36 PM, Mihaela Stefan wrote:
> > I tried that, too and it seemed to work. I extracted the ROIs from
> > ?h.aparc.annot and merged them into a single label with
> > mri_mergelabels then I ran mri_glmfit. Now I am not sure I used the
> > correct command to mask the search:
> >
> > mri_glmfit --y lh.g2v0.thickness.15.mgh --fsgd g2v0.fsgd dods --C
> > group.diff.mtx --surf fsaverage lh --label lh.22mask.label --glmdir
> > lh.group_diff_g2v0.glmdir
> >
> > So I used my own label instead of ?h.aparc.annot. Does the above
> > command look right?
> >
> > Thanks again!
> > Mihaela
> >
> > On Fri, Jul 22, 2016 at 12:34 PM, Douglas N Greve
> > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
> >
> >     What was your visualization command? You should probably run
> >     mri_vol2surf with --projfract 0.5 and --interp nearest to get a
> >     surface
> >     map. But it begs the question as to why you would do binarize the
> >     aparc+aseg to get surface ROIs (you should just use the
> >     ?h.aparc.annot).
> >     doug
> >
> >     On 07/22/2016 10:38 AM, Mihaela Stefan wrote:
> >     > Hi Doug,
> >     >
> >     > I used this command:
> >     > mri_binarize --match 1035 1028 1003 1027 1031 1008 1002 1026
> >     1018 1020
> >     > 1019 --i aparc+aseg.mgz --o lh22mask.mgz
> >     >
> >     > When I checked it first time, I opened it as a volume and it looked
> >     > okay to me.
> >     > Now I was able to view it in tksurfer but it looks weird. See
> >     attachment.
> >     >
> >     >
> >     > Alternatively, I was able to create a label with mri_mergelabels:
> >     > mri_mergelabels -i rh.insula.label -i rh.superiorfrontal.label -i
> >     > rh.caudalmiddlefrontal.label -i rh.rostralmiddlefrontal.label -i
> >     > rh.supramarginal.label -i rh.inferiorparietal.label -i
> >     > rh.caudalanteriorcingulate.label -i
> >     rh.rostralanteriorcingulate.label
> >     > -i rh.parsopercularis.label -i rh.parstriangularis.label -i
> >     > rh.parsorbitalis.label -o rh.22mask.label
> >     >
> >     > The mri_glmfit command seemed to have run successfully. However,
> the
> >     > results from the ROI analysis are almost identical with the whole
> >     > brain analysis. I find that surprising. Does it make sense
> >     statistically?
> >     >
> >     > Here is the command I used for the whole brain analysis:
> >     > mri_glmfit --y lh.g2v0.thickness.15.mgh --fsgd g2v0.fsgd dods --C
> >     > group.diff.mtx --surf fsaverage lh --cortex --glmdir
> >     > lh.group_diff_g2v0WB.glmdir
> >     >
> >     > And the command with the label for the ROI analysis:
> >     > mri_glmfit --y lh.g2v0.thickness.15.mgh --fsgd g2v0.fsgd dods --C
> >     > group.diff.mtx --surf fsaverage lh --label lh.22mask.label --glmdir
> >     > lh.group_diff_g2v0.glmdir
> >     >
> >     > Thanks!
> >     > Mihaela
> >     >
> >     >
> >     > On Thu, Jul 21, 2016 at 5:55 PM, Douglas N Greve
> >     > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> >     <mailto:gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
> >     >
> >     >     How did you create the mask? It should be a surface overlay in
> >     >     fsaverage
> >     >     space, ie, you should be able to view it with
> >     >
> >     >     tksurfer fsaverage lh inflated -ov mask.mgz -fminmax .1 1
> >     >
> >     >     On 07/21/2016 01:51 PM, Mihaela Stefan wrote:
> >     >     > Hello freesurfers,
> >     >     >
> >     >     > I would like to use mri_glmfit with --mask but I get this
> >     error:
> >     >     > dimension mismatch 1 between y and mask.
> >     >     > I created a binary mask from 22 aparc labels (using
> >     >     mri_binarize) and
> >     >     > I would like to run a surface-based analysis only on those
> >     regions.
> >     >     > The command I use is:
> >     >     >
> >     >     > mri_glmfit --y lh.g2v0.thickness.15.mgh --fsgd g2v0.fsgd
> >     dods --C
> >     >     > lh.group.diff.mtx --surf fsaverage lh --mask lh22mask.mgz
> >     --glmdir
> >     >     > lh.group_diff_g2v0.glmdir
> >     >     >
> >     >     > The input file was generated with this command:
> >     >     > mris_preproc --fsgd g2v0.fsgd --cache-in
> >     thickness.fwhm15.fsaverage
> >     >     > --target fsaverage --hemi lh --out lh.g2v0.thickness.15.mgh
> >     >     >
> >     >     > From the error, it seems that I am not using the right
> >     input file.
> >     >     > What kind of input file should be used with a mask?
> >     >     >
> >     >     > I also thought to use --label but I am not sure how to
> >     combine my 22
> >     >     > labels in one single label. mris_label2annot can combine them
> >     >     but the
> >     >     > output is an annotation file not a label.
> >     >     >
> >     >     > As a note, we will want to do FDR correction, not MC.
> >     >     >
> >     >     > Thanks!
> >     >     > Mihaela
> >     >     >
> >     >     >
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> >     >     --
> >     >     Douglas N. Greve, Ph.D.
> >     >     MGH-NMR Center
> >     > gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> >     <mailto:gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu
> >>
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> >     --
> >     Douglas N. Greve, Ph.D.
> >     MGH-NMR Center
> >     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> >     Phone Number: 617-724-2358 <tel:617-724-2358>
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> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
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>
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