Hi Again,

  (apologies for the many posts): I should add that none of this happens 
(and everything works fine - no warning and small clusters which look 
reasonable) if I use version 5.3.

Thank you,

Nicola

On 7/22/2016 2:10 PM, Nicola Toschi wrote:
> Hi,
>
> thanks - I tried using "abs" as well as a higher threshold, however the
> large, whole-brain cluster (as well as the warning messages) still remains.
>
> Do the warnings:
>
> WARNING: unrecognized mri_glmfit cmd option mri_glmfit.bin
> WARNING: 251446 NaNs found in volume
>
> give any clues?
>
> The strange thing is that everything is fine (small clusters and no
> warning) when I use t-tests )i.e. just the first or second line of the F
> test).
>
> Thanks a lot for your time,
>
> Nicola
>
>
> On 07/21/2016 11:53 PM, Douglas N Greve wrote:
>> Try using abs instead of pos. abs (absolute) is more appropriate since
>> an F test is unsigned. Also, I would go with a threshold of 2 and not
>> 1.3. I'm just now finding out that such a low threshold can cause a
>> lot of false postives on real data.
>>
>>
>> On 07/21/2016 05:32 PM, Nicola Toschi wrote:
>>> Hi,
>>>
>>> thanks for your reply. The mri_glmfit-sim was pasted below, here it
>>> is the dereferenced version:
>>>
>>>
>>> /usr/local/freesurfer6dev/bin/mri_glmfit-sim --glmdir
>>> design_3groups_AgeGenderIq_area_lh_fwhm0_pial --cache 1.3 pos
>>>
>>>
>>> thanks again,
>>>
>>> Nicola
>>>
>>> On 7/21/2016 11:13 PM, Douglas N Greve wrote:
>>>> That is the mri_glmfit command, I need the mri_glmfit-sim. Also,
>>>> please do not include variables, just the full command with all
>>>> dereferenced args
>>>>
>>>> On 07/21/2016 03:28 PM, Nicola Toschi wrote:
>>>>> Hi,
>>>>>
>>>>> here it is (I also pasted the mri_glmfit line):
>>>>>
>>>>> /odir=${prefix}_${meas}_${h}_fwhm${s}_${surf} #name output directory//
>>>>> //
>>>>> //mri_glmfit --y ${h}.fwhm${s}.${list}.${meas}.mgh --X ${matrix} \//
>>>>> //--C ${C1} \//
>>>>> //--glmdir ${odir} --surf fsaverage ${h} ${surf}//
>>>>> //
>>>>> //*/usr/local/freesurfer6dev/bin/mri_glmfit-sim --glmdir ${odir}
>>>>> --cache ${t} pos*//*
>>>>> */
>>>>> Note: it is the same code i use for the t-tests, which appear to
>>>>> work fine.
>>>>>
>>>>> The content of the file ${C1} is
>>>>>
>>>>> 1       -1      0       0       0       0
>>>>> 1       0      -1       0       0       0
>>>>>
>>>>>
>>>>> Thanks in advance!
>>>>>
>>>>> Nicola
>>>>>
>>>>>
>>>>>
>>>>> On 7/21/2016 5:38 PM, Douglas N Greve wrote:
>>>>>> what is your mri_glmfit-sim command line?
>>>>>>
>>>>>> On 07/20/2016 05:56 PM, Nicola Toschi wrote:
>>>>>>> Hi List,
>>>>>>>
>>>>>>> I am getting a couple of strange error when running a 3-group
>>>>>>> F-test.
>>>>>>>
>>>>>>> WARNING: unrecognized mri_glmfit cmd option mri_glmfit.bin
>>>>>>> WARNING: 251446 NaNs found in volume
>>>>>>> analysis/Ftest/cache.th20.pos.sig.cluster.mgh...
>>>>>>>
>>>>>>> And as a result, I consistently get huge clusters:
>>>>>>>
>>>>>>> # ClusterNo  Max   VtxMax   Size(mm^2)  MNIX   MNIY MNIZ CWP
>>>>>>> CWPLow    CWPHi   NVtxs    WghtVtx   Annot
>>>>>>>        1          inf       0  63247.45    -38.8  -19.0 66.9 0.00010
>>>>>>> 0.00000  0.00020  98722         inf  precentral
>>>>>>>
>>>>>>> However, this doesn't happen when running t-tests on the same data.
>>>>>>> Still, I think my F-contrast is correct (see below).
>>>>>>>
>>>>>>> Thanks in advance for any advice!
>>>>>>>
>>>>>>> Nicola
>>>>>>>
>>>>>>> PS:
>>>>>>>
>>>>>>> my F-contrast looks like this:
>>>>>>>
>>>>>>> 1       -1      0       0       0       0
>>>>>>> 1       0      -1       0       0       0
>>>>>>>
>>>>>>> and my design matrix looks like this:
>>>>>>>
>>>>>>> 0       0       1       1       179     110
>>>>>>> 0       0       1       1       193     103
>>>>>>> 0       0       1       1       176     108
>>>>>>> 0       0       1       1       198     94
>>>>>>> 0       1       0       1       186     87
>>>>>>> 0       1       0       1       217     83
>>>>>>> .....
>>>>>>>
>>>>>>> and my versions are
>>>>>>>
>>>>>>> # $Id: mri_surfcluster.c,v 1.57 2014/03/06 17:02:46 greve Exp $
>>>>>>> # $Id: mrisurf.c,v 1.776 2015/12/17 18:09:34 fischl Exp $
>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>> _______________________________________________
>>>>>>> Freesurfer mailing list
>>>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>>>
>>>>>>>
>>>
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