Hi Doug,
thank you veru much for the answr.
Please what do you mean by " an emperical question that depends on your data"? For example:
I have two groups of participants. I ran cortical thickness analysis in Qdec to study the differnce between the groups in cortical thickness:
1. Monte carlo simulation reported differnce between the groups ( p<0.05 ) in the precentral gyrus and the paracentral gyrus
2. FDR reported no diffwernce between the groups ( p<0.05)
Depending on pathology. I expect a differnce in the orecentral gyrus. How can I explain the results of FDR and mote carlo simulation? Does "empirical " means to follow the results that support the hypothesis?
John Anderson
Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
Sent: Wednesday, July 06, 2016 at 1:44 PM
From: "Douglas N Greve" <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] Qdec-correction for multiple comparison
From: "Douglas N Greve" <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] Qdec-correction for multiple comparison
There is no recommendation between FDR and monte carlo. The question of
which one is "better" is an emperical question that depends on your data.
On 06/29/2016 06:38 AM, John Anderson wrote:
> Dear FS experts,
> I will re post this thread again looking for your help and support:
> I ran cortical thickness analysis between two groups using Qdec and I
> want to correct the results for multiple comparison.
> In Qdec there are two choices to correct the data for multiple
> comparison (FDR and montecarlo) . Which method do you recommend to
> correct the results of cortical thickness analysis? Are there any
> rules that I need to follow when I choose my method to correct the
> results for multiple comparison ( i.e FDR or montecarlo)
> Thank you very much for any comment!
> John Anderson
>
> Senior Research Associate
> Psychological and Brain Sciences Dept.
> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
> Phone: +1 (603) 646-9834
> Fax: +1 (603) 646-1419
>
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
--
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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which one is "better" is an emperical question that depends on your data.
On 06/29/2016 06:38 AM, John Anderson wrote:
> Dear FS experts,
> I will re post this thread again looking for your help and support:
> I ran cortical thickness analysis between two groups using Qdec and I
> want to correct the results for multiple comparison.
> In Qdec there are two choices to correct the data for multiple
> comparison (FDR and montecarlo) . Which method do you recommend to
> correct the results of cortical thickness analysis? Are there any
> rules that I need to follow when I choose my method to correct the
> results for multiple comparison ( i.e FDR or montecarlo)
> Thank you very much for any comment!
> John Anderson
>
> Senior Research Associate
> Psychological and Brain Sciences Dept.
> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
> Phone: +1 (603) 646-9834
> Fax: +1 (603) 646-1419
>
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
--
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422
Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.
_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
