Hi Doug and Martin,

Thanks both for your responses. I am working with  PK11195, AV-1451,
and PiB. In general, the standard bbregister routine with init-fsl
works well for AV-1451 (adjustments needed in 30% of cases) and PiB
(best performance), but it completely failed with the PK data which
was acquired on the same scanner. I tried running the registration
using the mean image (mri_concat --mean) but it did not help too.

All that being said, mri_coreg works extremely well for the PK11195
(only 3 manual adjustments needed so far for > 50 scans), so I am very
grateful for this tool :)

If I want to run the analyses of the various PET data in the same
study, will it be of concern that I am using a mix of boundary-based
(AV and PIB) and normalised mutual information (PK)?

Best Wishes,
Elijah


Re: [Freesurfer] mri_coreg !
<http://www.mail-archive.com/search?l=freesurfer@nmr.mgh.harvard.edu&q=subject:%22Re%5C%3A+%5C%5BFreesurfer%5C%5D+mri_coreg+%5C%21%22&o=newest>

Martin Reuter 
<http://www.mail-archive.com/search?l=freesurfer@nmr.mgh.harvard.edu&q=from:%22Martin+Reuter%22>
Mon, 16 May 2016 13:23:13 -0700
<http://www.mail-archive.com/search?l=freesurfer@nmr.mgh.harvard.edu&q=date:20160516>

Hi,

just wanted to mention that the --cost NMI (normalized mutual
information) and MI implementations in mri_robust_register are the same
as spm_coreg and now mri_coreg (if the -nosym flag is specified in
robust register, else it is registering in a symmetric midspace instead
into the target space). If you have cases where robust_register fails,
but the other tools work, let me know, because that could indicate a bug
in my code.

Thanks, Martin


On 05/16/2016 03:19 PM, Douglas N Greve wrote:
> It is my implementation of the spm_coreg program written by John
> Ashburner using normalized mutual information. I liked the spm program
> so much that I put the effort into replicating its behavior in C. My
> guess is that BBR was failing because the initialization was failing.
> Still I like mri_coreg for PET data because the blurriness can throw BBR
> off a bit. What kind of PET data do you have?
>
>
> On 05/16/2016 03:06 PM, Elijah Mak wrote:
>> Hi Doug,
>>
>> I just want to say that mri_coreg worked tremendously well for the
>> registration of some very blurry PET-PK data. I was not getting any
>> success with bbregister and init-fsl or mri_robust_register options.
>>
>> How does this technique differ from the boundary-based registration?
>>
>> Thanks a lot.
>>
>> Best Wishes,
>> Elijah
>>
>>
>>
>>
>>
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
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-- 
Martin Reuter, PhD
Assistant Professor of Radiology, Harvard Medical School
Assistant Professor of Neurology, Harvard Medical School
A.A.Martinos Center for Biomedical Imaging
Massachusetts General Hospital
Research Affiliate, CSAIL, MIT
Phone: +1-617-724-5652
Web  : http://reuter.mit.edu

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-- 

Elijah Mak, Gates Scholar

PhD Candidate *|* Psychiatry

University of Cambridge

Trinity College, Cambridge, CB2 1TQ
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