Hi Eugenio,

Thanks, the script worked.

Actually I only edited the medulla segmentation in 3 out of the 49 subjects
that I have. I suppose the original volumetric estimates for midbrain and
pons are still valid and I can just calculate and compare the new medulla
volumes for all subjects. Is that correct?

Jacky

2016-05-12 12:05 GMT+02:00 Eugenio Iglesias <e.igles...@bcbl.eu>:

> My email client is replacing the combination colon + right parenthesis by
> a smiley! If the same thing happened to you, please replace the smiley by a
> colon and a right parenthesis...
> Next time I'll just attach the code.
> Sorry for the inconvenience
>
> Juan Eugenio Iglesias
> Postdoctoral researcher BCBL
> www.jeiglesias.com
> www.bcbl.eu
>
> Legal disclaimer/Aviso legal/Lege-oharra: www.bcbl.eu/legal-disclaimer
>
> ------------------------------
> *From: *"Eugenio Iglesias" <e.igles...@bcbl.eu>
> *To: *"Jacky Lee" <cyle...@gmail.com>
> *Cc: *"Freesurfer support list" <Freesurfer@nmr.mgh.harvard.edu>
> *Sent: *Thursday, May 12, 2016 5:59:33 AM
>
> *Subject: *Re: [Freesurfer] Manual correction for brainstem module
>
> Of course! I haven't tested the code below, but I think it should work
> right away.
>
> Let's assume that FreeSurfer is installed in /usr/local/freesurfer/ (if
> not, replace the location in the code below). Also, you'd need to replace
> the name of your subject directory.
> Finally, I have assumed that brainstemSsLabels.v10.mgz was modified and
> saved as  brainstemSsLabels.v10.edited.mgz  (again, replace as needed).
>
>
> subjectdir='/mysubjectdir/';
> editedFileName='brainstemSsLabels.v10.edited.mgz';
>
> addpath /usr/local/freesurfer/matlab
>
> d=dir(subjectdir);
>
> for i=1:length(d)
>
>   tentativeSegFile=[subjectdir '/' d(i).name '/mri/' editedFileName];
>
>   if d(i).isdir && exist(tentativeSegFile,'file')
>
>     A=MRIread(tentativeSegFile);
>     MidbrainVol=8*sum(A.vol(:)==173);   % the eight is because each voxel
> of the segmentation has a volume equal to 0.125 cubic mm
>     PonsVol=8*sum(A.vol(:)==174);
>     MedullaVol=8*sum(A.vol(:)==175);
>     SCPvol=8*sum(A.vol(:)==178);
>
>     disp(['Subject ' d(i).name ', midbrain = ' num2str(MidbrainVol) ',
> pons = ' num2str(PonsVol) ', medulla = ' num2str(MedullaVol) ', SCP = '
> num2str(SCPvol)]);
>
>   end
>
> end
>
> One more thing: if you haven't edited anything around the SCP, I would use
> the original estimate for this structure. The reason is that, because the
> SCP is very thing, the voxel count is a much poorer approximation for the
> volume as computed by the code (i.e., using soft segmentations).
>
> Cheers,
>
> Eugenio
>
>
> Juan Eugenio Iglesias
> Postdoctoral researcher BCBL
> www.jeiglesias.com
> www.bcbl.eu
>
> Legal disclaimer/Aviso legal/Lege-oharra: www.bcbl.eu/legal-disclaimer
>
> ------------------------------
> *From: *"Jacky Lee" <cyle...@gmail.com>
> *To: *"Freesurfer support list" <Freesurfer@nmr.mgh.harvard.edu>
> *Cc: *"Eugenio Iglesias" <e.igles...@bcbl.eu>
> *Sent: *Thursday, May 12, 2016 10:32:24 AM
> *Subject: *Re: [Freesurfer] Manual correction for brainstem module
>
> Hi Eugenio,
>
> Yes please give me some advice on the matlab commands for this since I am not 
> very familiar with matlab...
>
> Cheers,
>
> Jacky
>
>
> Hi Jacky,
> this is a good question, and unfortunately there isn't a great answer to it.
> The volume is computed upong a probabilitic segmentation of the voxels that is
> not written to disk (this is very similar to what happens with aseg.mgz and
> aseg.stats). In order to properly update the volume estimates, you would have
> to know the probability that the inpainted voxels belong to the brainstem as
> estimated by the algorithm, which we don't currently write to disk.
> Another option would be to toss the volumes given by the algorithm, and 
> compute
> new volumes for all cases and brainstem structures using the hard
> segmentations. You would simply have to count the number of voxels labeled as
> midbrain, pons, SCP and medulla for each subject. You can easily do this e.g.
> with Matlab (let me know if you need help with this).
> Cheers,
> Eugenio
>
> Juan Eugenio Iglesias
> Postdoctoral researcher BCBL www.jeiglesias.com www.bcbl.eu
>
> Legal disclaimer/Aviso legal/Lege-oharra: www.bcbl.eu/legal-disclaimer
>
>
> From: "Jacky Lee" <cyle...@gmail.com>
> To: "Freesurfer support list" <Freesurfer@nmr.mgh.harvard.edu>
> Sent: Monday, May 9, 2016 2:01:53 AM
> Subject: [Freesurfer] Manual correction for brainstem module
>
> Hi freesurfer experts,
>
> I have successfully run the brainstem module for some subjects. On visual
> checking, I can see there are voxels with T1 hypointense lesions mislabelled 
> as
> non-brainstem tissue. I manually corrected them on the
> brainstemSsLabels.v10.mgz on Freeview. Then how do I obtain this new corrected
> volume of the brainstem substructures?
>
> Thanks.
>
> Regards,
>
> Jacky
>
>
>
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