hello experts

i have some question to you

What is the meaning about cortical thickness alteration (increase or
decrease)

a few days ago i read these sentences

Deviations from these patterns can be used as diagnostic indicators for brain
disorders <http://en.citizendium.org/wiki/Brain_disorder>: While Alzheimer's
disease <http://en.citizendium.org/wiki/Alzheimer%27s_disease>, even very
early on, is characterized by pronounced cortical thinning[4]
<http://en.citizendium.org/wiki/Cortical_thickness#cite_note-Dickerson2009-4>
, Williams syndrome
<http://en.citizendium.org/wiki?title=Williams_syndrome&action=edit&redlink=1>
patients
exhibit an increase in cortical thickness of about 5-10% in some regions [5]
<http://en.citizendium.org/wiki/Cortical_thickness#cite_note-Thompson2005-5>,
and lissencephalic <http://en.citizendium.org/wiki/Lissencephalic> patients
show drastic thickening, up to several centimetres in occipital regions[6]
<http://en.citizendium.org/wiki/Cortical_thickness#cite_note-Guerrini2006-6>.
from wiki

i wonder increased or reduced cortex depended on disorder?

plz answer me

2016-02-06 0:27 GMT+09:00 Bruce Fischl <fis...@nmr.mgh.harvard.edu>:

> Hi A-reum
>
> we use average Euclidean distance from gray to white and visa-versa. There
> are other (variational) techniques that we have messed around with, but
> none of our experiments have shown that they are any better, so we have
> stuck with the simplest thing.
>
> cheers
> Bruce
>
>
> On Fri, 5 Feb 2016, A-reum Min wrote:
>
> hello experts
>>
>> i have some question to you
>>
>> What method do you use when measuring the cortical thickness?
>>
>> (ex. Euclidean distance of a Danielsson Distance Map or 3D Eikonal
>> equation?)
>>
>> plz answer me.
>>
>> 2016-01-17 0:53 GMT+09:00 A-reum Min <naniy...@gmail.com>:
>>       Thank you for u r answer.
>> I have some question to you.
>>
>> i compared two groups(patients VS control)
>>
>> How can i extract the total vertices(ex.#1 vertex : cortical thickness
>> value) to 1 subject(patient) and average of patients ?
>> I want to compared asymmetry of brain (lateralization). So, i really
>> necessary above value(cortical thickness value of vertex).
>>
>> plz answer me.
>>
>> Thank you.
>>
>>
>> 2016-01-17 0:22 GMT+09:00 Bruce Fischl <fis...@nmr.mgh.harvard.edu>:
>>       Hi Areum
>>
>>       every brain will have a somewhat different number of
>>       vertices depending on size and geometry. If you want them
>>       to be comparable you need to map them into the fsaverage
>>       space using e.g. the -qcache switch to recon-all (or
>>       mri_surf2surf directly if you prefer).
>>
>>       cheers
>>       Bruce
>>
>>
>>       On Sat, 16 Jan 2016, A-reum Min wrote:
>>
>>             Hello expert.
>>             I'm Areum.
>>
>>             I have some question to you.
>>
>>             A weeks ago, i compared two groups (OSA
>>             patients VS control) and then the
>>             number of vertices were confirmed.
>>
>>             Each group has the same number of
>>             vertices.(176416) -experiment 1.
>>
>>             And yesterday, i compared two groups(partial
>>             sleep deprivation:PSD VS
>>             control) and then the number of vertices were
>>             confirmed.
>>
>>             Each group has the same number of
>>             vertices(169548) -experiment 2.
>>
>>
>>             1) Why isn't the same number of total
>>             vertices? is it related rain size?
>>
>>
>>             2) How can i extract the number of total
>>             vertices(ex.#1 vertex : cortical
>>             thickness value) to 1 subject(PSD) and average
>>             of PSD ?
>>             I want to compared asymmetry of brain
>>             (lateralization). So, i really
>>             necessary above value(cortical thickness value
>>             of vertex).
>>
>>             plz answer me.
>>
>>             Thank you.
>>
>>
>>             2016-01-07 3:52 GMT+09:00 Bruce Fischl
>>             <fis...@nmr.mgh.harvard.edu>:
>>                   Hi A-reum
>>
>>                   did you talk to the Wash U group? If you
>>             have nifti files they
>>                   can be processed using recon-all (i.e.
>>             recon-all -i <full path
>>                   to nifti file> -s <subject id> -sd
>>             <directory to contain all
>>                   subjects> -all)
>>
>>                   cheers
>>                   Bruce
>>
>>
>>                   On Tue, 29 Dec 2015, A-reum Min wrote:
>>
>>                         hello experts!my name is areum.
>>                         i have some question to you.i have
>>             never seen before
>>                         these NIFTI
>>                         format(fig.1.png)
>>                         I want to see these data
>>             subjects's cortical
>>                         thickness using qdec.
>>                         how can i to do? plz answer me
>>
>>                         2015-12-25 2:16 GMT+09:00 Bruce
>>             Fischl
>>                         <fis...@nmr.mgh.harvard.edu>:
>>                               Hi A-reum
>>
>>                               you should probably ask the
>>             Wash U HCP group.
>>                         I'll cc Matt
>>                               Glasser who might be able to
>>             answer your
>>                         question
>>                               cheers
>>                               Bruce
>>
>>                               On Thu, 24 Dec 2015, A-reum
>>             Min wrote:
>>
>>                                     hello experts!my name
>>             is areum.
>>                                     i have some question
>>             to you.
>>                                     a few days ago i was
>>             down load HCP(human
>>                         connectom
>>                                     project) data.
>>                                     but.. how can i use
>>             these HCP format.
>>                                     i have never seen
>>             before these
>>                         format(fig.1.png)
>>                                     I want to see HCP data
>>             subjects's
>>                         cortical thickness
>>                                     using qdec.
>>                                     how can i to do?
>>                                     plz answer me
>>
>>                                     2015-11-10 7:49
>>             GMT+09:00 A-reum Min
>>                                     <naniy...@gmail.com>:
>>                                           Hello experts!
>>                                     I have some question
>>             to you..
>>
>>                                     I don't need to show
>>             up so small blue
>>                         regions(fig.1
>>                                     blue region)
>>
>>                                     How can i control
>>             these?
>>
>>                                     2015-11-10 7:41
>>             GMT+09:00 Douglas N
>>                         Greve
>>
>>             <gr...@nmr.mgh.harvard.edu>:
>>                                           Hi, please
>>             create a new thread
>>                         since this is a
>>                                     new topic.
>>                                           Also, I don't
>>                                           understand your
>>             question so please
>>                         elaborate.
>>
>>                                           On 11/09/2015
>>             05:34 AM, A-reum Min
>>                         wrote:
>>                                           > Hello experts!
>>                                           >
>>                                           > i have some
>>             question to you..
>>                                           >
>>                                           > How can i
>>             control the cluster
>>                         size?
>>                                           >
>>                                           > My cluster
>>             threshold is 1.
>>                                           >
>>                                           > then, too many
>>             blue regions (as
>>                         shown
>>                                     fig.1).
>>                                           >
>>                                           > so, i want to
>>             control cluster
>>                         threshold 1-->
>>                                     cluster
>>                                           threshold 5.
>>                                           >
>>                                           > 2015-11-08
>>             20:44 GMT+09:00
>>                         A-reum Min
>>
>>             <naniy...@gmail.com
>>                                           >
>>             <mailto:naniy...@gmail.com>>:
>>                                           >
>>                                           >     Hello
>>             bruce!
>>                                           >
>>                                           >     I solve
>>             the problem for your
>>                         answer.
>>                                           >
>>                                           >     And.. i
>>             have some question
>>                         to you..
>>                                           >
>>                                           >     How can i
>>             control the
>>                         cluster size?
>>                                           >
>>                                           >     My cluster
>>             threshold is 1.
>>                                           >
>>                                           >     then, too
>>             many blue regions
>>                         (as shown
>>                                     fig.1).
>>                                           >
>>                                           >     so, i want
>>             to control
>>                         cluster threshold
>>                                     1--> cluster
>>                                           threshold 5.
>>                                           >
>>                                           >     How can i
>>             to do?
>>                                           >
>>                                           >
>>                                           >
>>                                           >
>>                                           >
>>                                           >     2015-11-05
>>             22:22 GMT+09:00
>>                         Bruce Fischl
>>                                           >
>>              <fis...@nmr.mgh.harvard.edu
>>
>>
>>             <mailto:fis...@nmr.mgh.harvard.edu>>:
>>                                           >
>>                                           >         are
>>
>>
>>
>>             /usr/local/freesurfer/subjects/OSA/0165766_1/P016001.dcm
>>                                           >         and
>>
>>
>>
>>             /usr/local/freesurfer/subjects/OSA/0165766_1/P016002.dcm
>>                                           >         images
>>             from *different*
>>                         series or
>>                                     from the
>>                                           *same* series?
>>             If
>>                                           >         they
>>             are in the same
>>                         series than
>>                                     that explains
>>                                           what is
>>                                           >
>>              happening. You should
>>                         only give
>>                                     recon-all a
>>                                           single file from
>>                                           >         any
>>             one acquisition - it
>>                         will figure
>>                                     out the
>>                                           rest of the
>>             files
>>                                           >         that
>>             are part of it.
>>                                           >
>>                                           >         cheers
>>                                           >         Bruce
>>                                           >
>>                                           >
>>                                           >         On
>>             Thu, 5 Nov 2015,
>>                         A-reum Min
>>                                     wrote:
>>                                           >
>>                                           >
>>              hello experts.
>>                                           >             i
>>             have some question
>>                         to  you...
>>                                           >
>>                                           >
>>              when i enter the
>>                         recon-all -i
>>                                     /paht~
>>                                           >
>>                                           >
>>              error showed up....
>>                         like below
>>                                     one..
>>                                           >
>>                                           >
>>              how can i to fix it?
>>                                           >
>>                                           >
>>              [areum@localhost
>>                         0165766_1]#
>>                                     recon-all -i
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016001.dcm
>>                                           -i
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016002.dcm
>>                                           >
>>              -all -s sub002
>>                                           >
>>              Subject Stamp:
>>                                           >
>>
>>
>>
>>              freesurfer-Linux-centos6_x86_64-stable-pub-v5.3.0
>>                                           >
>>              Current Stamp:
>>                                           >
>>
>>
>>
>>              freesurfer-Linux-centos6_x86_64-stable-pub-v5.3.0
>>                                           >
>>              INFO: SUBJECTS_DIR
>>                         is
>>                                           >
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1
>>                                           >
>>              Actual
>>                         FREESURFER_HOME
>>                                     /usr/local/freesurfer
>>                                           >
>>              Linux
>>                         localhost.localdomain
>>
>>             2.6.32-504.el6.x86_64 #1 SMP
>>                                           >
>>              Wed Oct 15 04:27:16
>>                                           >
>>              UTC 2014 x86_64
>>                         x86_64 x86_64
>>                                     GNU/Linux
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/sub002
>>                                           >
>>                                           >
>>             mri_convert
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016001.dcm
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.mgz
>>                                           >
>>                                           >
>>                                           >
>>              mri_convert
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016001.dcm
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.mgz
>>                                           >
>>                                           >
>>              $Id: mri_convert.c,v
>>                         1.179.2.7
>>                                     2012/09/05
>>                                           21:55:16 mreuter
>>                                           >
>>              Exp $
>>                                           >
>>              reading from
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016001.dcm...
>>                                           >
>>              Starting
>>                         DICOMRead2()
>>                                           >
>>              dcmfile =
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016001.dcm
>>                                           >
>>              dcmdir =
>>
>>
>>             /usr/local/freesurfer/subjects/OSA/0165766_1
>>                                           >
>>              Ref Series No = 3
>>                                           >
>>              Found 247 files,
>>                         checking for
>>                                     dicoms
>>                                           >
>>              Found 244 dicom
>>                         files in series.
>>                                           >
>>              First Sorting
>>                                           >
>>              Computing Slice
>>                         Direction
>>                                           >
>>              Vs: -0.8 0 0
>>                                           >
>>              Vs: -1 0 0
>>                                           >
>>              Second Sorting
>>                                           >
>>              Counting frames
>>                                           >
>>              nframes = 1
>>                                           >
>>              nslices = 244
>>                                           >
>>              ndcmfiles = 244
>>                                           >             PE
>>             Dir = ROW (dicom
>>                         read)
>>                                           >
>>              TransferSyntaxUID:
>>
>>             --1.2.840.10008.1.2.1--
>>                                           >
>>              Loading pixel data
>>                                           >
>>              TR=7.70, TE=3.37,
>>                         TI=400.00,
>>                                     flip
>>                                           angle=12.00
>>                                           >
>>              i_ras = (0, -1, 0)
>>                                           >
>>              j_ras = (0, 0, -1)
>>                                           >
>>              k_ras = (1, -0, 0)
>>                                           >
>>              writing to
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.mgz...
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/sub002
>>                                           >
>>                                           >
>>             mri_convert
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016002.dcm
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.mgz
>>                                           >
>>                                           >
>>                                           >
>>              mri_convert
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016002.dcm
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.mgz
>>                                           >
>>                                           >
>>              $Id: mri_convert.c,v
>>                         1.179.2.7
>>                                     2012/09/05
>>                                           21:55:16 mreuter
>>                                           >
>>              Exp $
>>                                           >
>>              reading from
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016002.dcm...
>>                                           >
>>              Starting
>>                         DICOMRead2()
>>                                           >
>>              dcmfile =
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/P016002.dcm
>>                                           >
>>              dcmdir =
>>
>>
>>             /usr/local/freesurfer/subjects/OSA/0165766_1
>>                                           >
>>              Ref Series No = 3
>>                                           >
>>              Found 247 files,
>>                         checking for
>>                                     dicoms
>>                                           >
>>              Found 244 dicom
>>                         files in series.
>>                                           >
>>              First Sorting
>>                                           >
>>              Computing Slice
>>                         Direction
>>                                           >
>>              Vs: -0.8 0 0
>>                                           >
>>              Vs: -1 0 0
>>                                           >
>>              Second Sorting
>>                                           >
>>              Counting frames
>>                                           >
>>              nframes = 1
>>                                           >
>>              nslices = 244
>>                                           >
>>              ndcmfiles = 244
>>                                           >             PE
>>             Dir = ROW (dicom
>>                         read)
>>                                           >
>>              TransferSyntaxUID:
>>
>>             --1.2.840.10008.1.2.1--
>>                                           >
>>              Loading pixel data
>>                                           >
>>              TR=7.70, TE=3.37,
>>                         TI=400.00,
>>                                     flip
>>                                           angle=12.00
>>                                           >
>>              i_ras = (0, -1, 0)
>>                                           >
>>              j_ras = (0, 0, -1)
>>                                           >
>>              k_ras = (1, -0, 0)
>>                                           >
>>              writing to
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.mgz...
>>                                           >
>>
>>
>>              #--------------------------------------------
>>                                           >
>>              #@# MotionCor Thu
>>                         Nov  5
>>                                     02:27:17 PST 2015
>>                                           >
>>              Found 2 runs
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.mgz
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.mgz
>>                                           >
>>              Checking for
>>                         (invalid)
>>                                     multi-frame inputs...
>>                                           >
>>              Checking for
>>                         (invalid)
>>                                     multi-frame inputs...
>>                                           >
>>
>>
>>
>>              #-----------------------------------------------
>>                                           >
>>
>>
>>
>>              /usr/local/freesurfer/subjects/OSA/0165766_1/sub002
>>                                           >
>>                                           >
>>             mri_robust_template
>>                         --mov
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.mgz
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.mgz
>>                                           >
>>              --average 1
>>                         --template
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/rawavg.mgz
>>                                           >
>>              --satit
>>                                           >
>>              --inittp 1 --fixtp
>>                         --noit
>>                                     --iscale
>>                                           >
>>      --iscaleout/usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig
>>             /
>>                         0
>>                                     0
>>                                           1-iscale.txt
>>                                           >
>>      /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002-iscale
>>             .
>>                         t
>>                                     x
>>                                           t
>>                                           >
>>              --subsample 200
>>                         --lta
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.lta
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.lta
>>                                           >
>>                                           >
>>                                           >
>>              $Id:
>>                         mri_robust_template.cpp,v
>>                                     1.37.2.2
>>                                           2012/10/10
>>                                           >
>>              19:59:06 mreuter Exp
>>                         $
>>                                           >
>>                                           >
>>              --mov: Using
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.mgz
>>                                           >             as
>>                                           >
>>              movable/source
>>                         volume.
>>                                           >
>>              --mov: Using
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.mgz
>>                                           >             as
>>                                           >
>>              movable/source
>>                         volume.
>>                                           >
>>              Total: 2 input
>>                         volumes
>>                                           >
>>              --average: Using
>>                         method 1 for
>>                                     template
>>                                           computation.
>>                                           >
>>              --template: Using
>>                                           >
>>
>>
>>
>>
>>  /usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/rawavg.mgz
>>                                           >             as
>>                                           >
>>              template output
>>                         volume.
>>                                           >
>>              --satit: Will
>>                         estimate SAT
>>                                     iteratively!
>>                                           >
>>              --inittp: Using TP 1
>>                         as target
>>                                     for
>>                                           initialization
>>                                           >
>>              --fixtp: Will map
>>                         everything to
>>                                     init TP!
>>                                           >
>>              --noit: Will output
>>                         only first
>>                                     template (no
>>                                           iterations)!
>>                                           >
>>              --iscale: Enableing
>>                         intensity
>>                                     scaling!
>>                                           >
>>              --iscaleout: Will
>>                         perform
>>                                     intensity scaling
>>                                           and output
>>             results
>>                                           >
>>              --subsample: Will
>>                         subsample if
>>                                     size is
>>                                           larger than 200
>>             on
>>                                           >
>>              all axes!
>>                                           >
>>              --lta: Will output
>>                         LTA
>>                                     transforms
>>                                           >
>>              reading source
>>                                           >
>>
>>
>>
>>
>>  '/usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.mgz'...
>>                                           >
>>              converting source
>>                                           >
>>
>>
>>
>>
>>  '/usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/001.mgz'
>>                                           >             to
>>                                           >
>>              bspline ...
>>                                           >
>>              MRItoBSpline degree
>>                         3
>>                                           >
>>              reading source
>>                                           >
>>
>>
>>
>>
>>  '/usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.mgz'...
>>                                           >
>>              converting source
>>                                           >
>>
>>
>>
>>
>>  '/usr/local/freesurfer/subjects/OSA/0165766_1/sub002/mri/orig/002.mgz'
>>                                           >             to
>>                                           >
>>              bspline ...
>>                                           >
>>              MRItoBSpline degree
>>                         3
>>                                           >
>>                                           >
>>                          MultiRegistration::initializing
>>                                     Xforms (init
>>                                           1 , maxres 0
>>                                           >             ,
>>             iterate 5 ,
>>                                           >
>>              epsit 0.01 ) :
>>                                           >
>>                                           >
>>              [init]
>>                         =========================
>>                                     TP 2 to TP
>>                                           1
>>                                           >
>>                          ==============================
>>                                           >
>>                   Register TP
>>                         2 (
>>                                           >
>>
>>
>
>
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-- 
*------------------------------------------------------------*
*Areum Min*
Medical Image Processing Lab.
Department of Biomedical Engineering, Yonsei Univ.
218 San-hak Hall, 1 Yeonsedae-gil, Heungeop-myeon, Wonju, Gangwon, Korea
Office  : +82-33-760-2499
Mobile : +82-10-3428-0608
E-Mail : n <esth...@nate.com>aniy...@gmail.com
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