Hi Bruce (and the freesurfer community),

Thanks for your reply! Would it be possible to get more details on the process 
of how I might go about correcting these volumes myself? It would be ideal if I 
had the volumes prior to entering it into my statistical model (and thus I’d 
prefer not to use head size as a regressor if possible). When you say ‘dividing 
it out’, is this simply taking the regional volumes and dividing it by eTIV to 
obtain a proportion? What are the downsides to approaching it in this manner 
vs. using it as a regressor?

Many thanks,

Christina



> On Jan 11, 2016, at 12:46 PM, Bruce Fischl <fis...@nmr.mgh.harvard.edu> wrote:
> 
> Hi Christina
> 
> we don't correct any volumes for head size - we just provide the information 
> for you to do it yourself. I think including it as a regressor is more common 
> than dividing it out, but perhaps others can comment.
> 
> cheers
> Bruce
> On Mon, 11 Jan 2016, Christina van den Brink wrote:
> 
>> Hello,
>> I have a question regarding volume-correction for the morphometry stats
>> obtained via recon-all. I’ve noted that eTIV is derived using the atlas
>> scaling factor in order to account for head size. I’m wondering whether the
>> other volumes given, e.g. TotalGray or lhCorticalWhiteMatter, have also been
>> corrected for head size? If not, is there a recommended method in which to
>> do so so that regional volumes can be compared between participants?
>> Many thanks for your help!
>> Best,
>> Christina
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