Thanks a lot Bruce.
 Cheers

2016-01-11 14:43 GMT+01:00 Bruce Fischl <fis...@nmr.mgh.harvard.edu>:

> Hi Pietro
>
> ICV (or eTIV) is computed using Randy Buckner's method, so you can cite
> his paper. Correcting for whole brain volume is certainly a reasonable
> thing to do but note that then you are testing a somewhat different
> hypothesis (that local atrophy is faster than whole-brain atrophy, as
> opposed to whether atrophy exists at all)
>
> cheers
> Bruce
>
>
>
> On Mon, 11 Jan 2016, pietro de rossi wrote:
>
> Dear FreeSurfers,
>> I am editing a paper on subcortical volumes in deficit schizophrenia after
>> some reviewers' comments.
>> On of them suggested me to correct the volumes of subcortical structures
>> for
>> whole brain volume instead of intracranial volume. In the reviewer's
>> opinion
>> ICV  estimated by FreeSurfer 5.1 has a bad quality and is not reliable.
>> However,  neither the reviewer provides any evidence, nor I could find
>> any...
>> Is there any evidence for this?
>>
>> Thanks in advance,
>>
>> Pietro
>>
>> --
>> Pietro De Rossi, MD
>> -------------------------------------
>> Sapienza Università di Roma, Facoltà di Medicina e Psicologia,
>> Dipartimento
>> NESMOS (Neuroscienze, Salute Mentale, Organi di Senso), Ospedale
>> Sant'Andrea, Via di Grottarossa 1035-1039, 00189 Roma
>>
>> NESMOS Department (Neurosciences, Mental Health and Sensory Functions),
>> School of Medicine and Psychology, Sapienza University, Sant’Andrea
>> Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy
>>
>> Laboratorio di Neuropsichiatria, Dipartimento di Neurologia Clinica e
>> Comportamentale, IRCCS Fondazione Santa Lucia, via Ardeatina 306 - 00179
>> Roma
>>
>> Tel. +39 (0)6 51501358
>>
>> Fax +39 (0)6 90280774
>>
>> web: http://www.neuropsichiatrialab.com
>>
>>
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-- 
Pietro De Rossi, MD
-------------------------------------
Sapienza Università di Roma, Facoltà di Medicina e Psicologia, Dipartimento
NESMOS (Neuroscienze, Salute Mentale, Organi di Senso), Ospedale
Sant'Andrea, Via di Grottarossa 1035-1039, 00189 Roma

NESMOS Department (Neurosciences, Mental Health and Sensory Functions),
School of Medicine and Psychology, Sapienza University, Sant’Andrea
Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy

Laboratorio di Neuropsichiatria, Dipartimento di Neurologia Clinica e
Comportamentale, IRCCS Fondazione Santa Lucia, via Ardeatina 306 - 00179
Roma

Tel. +39 (0)6 51501358

Fax +39 (0)6 90280774
web: http://www.neuropsichiatrialab.com
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