There are inevitable issues around the boundaries of the cluster. For 
small clusters, this can be a big deal. I would probably just use the 
fsaverage clusters on the control group after they have been mapped to 
fsaverage space (ie, run mris_preproc on the control group to get a 
stack, smooth it, then run mri_segstats with the stack as the input and 
the ocn.mgh file as the --seg.

doug


On 07/02/2015 03:21 AM, Jürgen Hänggi wrote:
> Dear FS experts
>
> in a former email
>
>
> http://www.mail-archive.com/freesurfer%40nmr.mgh.harvard.edu/msg23322.html
>
>
> it has been recommended that we should not map clusters found in an 
> analysis in the standard space
>
> back to the individual space due to resampling issues.
>
>
> In one of our study, we computed a correlation across patients and 
> controlls and get MC simulation corrected clusters, the individual 
> values of it can be found in the ….y.ocn.dat file.
>
> A reviewer suggested to do the correlation only across the patient 
> group and then transform these clusters into the native space in
>
> order to extract the values within these clusters for the control group.
>
>
> Therefore we would like to know the exact reason why this resampling 
> is not recommended. Is it related to the fact that the transform
>
> from the native to the standard space is not one-to-one?
>
>
> What you recommend to answer to this reviewer point?
>
>
> Thanks in advance
>
> Best regards
>
> Jürgen Hänggi
>
>
> ---------------------------------------------------------------------------
>
> Jürgen Hänggi, Ph.D.
>
> Division Neuropsychology
>
> Institute of Psychology
>
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>
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>
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>
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>
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>
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>
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>
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>
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>
> http://www.juergenhaenggi.ch (private website)
>
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-- 
Douglas N. Greve, Ph.D.
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