There are inevitable issues around the boundaries of the cluster. For small clusters, this can be a big deal. I would probably just use the fsaverage clusters on the control group after they have been mapped to fsaverage space (ie, run mris_preproc on the control group to get a stack, smooth it, then run mri_segstats with the stack as the input and the ocn.mgh file as the --seg.
doug On 07/02/2015 03:21 AM, Jürgen Hänggi wrote: > Dear FS experts > > in a former email > > > http://www.mail-archive.com/freesurfer%40nmr.mgh.harvard.edu/msg23322.html > > > it has been recommended that we should not map clusters found in an > analysis in the standard space > > back to the individual space due to resampling issues. > > > In one of our study, we computed a correlation across patients and > controlls and get MC simulation corrected clusters, the individual > values of it can be found in the ….y.ocn.dat file. > > A reviewer suggested to do the correlation only across the patient > group and then transform these clusters into the native space in > > order to extract the values within these clusters for the control group. > > > Therefore we would like to know the exact reason why this resampling > is not recommended. Is it related to the fact that the transform > > from the native to the standard space is not one-to-one? > > > What you recommend to answer to this reviewer point? > > > Thanks in advance > > Best regards > > Jürgen Hänggi > > > --------------------------------------------------------------------------- > > Jürgen Hänggi, Ph.D. > > Division Neuropsychology > > Institute of Psychology > > University of Zurich > > Binzmuehlestrasse 14, PO Box 25 > > 8050 Zurich, Switzerland > > 0041 44 635 73 97 (phone office) > > 0041 76 445 86 84 (phone mobile) > > 0041 44 635 74 09 (fax office) > > BIN 4.D.04 (office room number) > > j.haenggi[at]psychologie.uzh.ch (email) > > http://www.psychologie.uzh.ch/neuropsy/ (website) > > http://www.juergenhaenggi.ch (private website) > > > This e-mail (and any attachment/s) contains confidential > > and/or privileged information. If you are not the intended > > recipient (or have received this e-mail in error) please notify > > the sender immediately and destroy this e-mail. Any > > unauthorised copying, disclosure or distribution of the > > material in this e-mail is strictly forbidden. > > --------------------------------------------------------------------------- > > > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.