Hi Bruce,

yes, it is an mp2rage image.
I'm gonna work in your suggestions and see if it changes anything after 
rerunning the the recon-all process.

Thank you!
Cheers, Clara

----- Ursprüngliche Mail -----
Von: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
An: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
Gesendet: Dienstag, 30. Juni 2015 16:18:06
Betreff: Re: [Freesurfer] too much white matter

Hi Clara

the second control point (135, 152, 163) is outside the brainmask. You will 
need to correct the skull stripping first. In general I wouldn't put 
control points in that type of location as it is certainly partial volumed. 
I would try something like 139, 145, 163 instead (and maybe a couple around 
there).

Also, I assume the skull stripping failed as this is not the typical type 
of image we expect (since the background is so bright and noisy). Is it an 
mp2rage or something? There appears to be very little space between skull 
and brain so the stripping may be challenging, particularly in the 
orbitofrontal region where you had this control point (it looks like fat is 
shifting upwards either into or adjacent to brain)

cheers
Bruce

On Tue, 30 Jun 2015, Clara Kühn 
wrote:

> oh, and here are the Freesurfer coordinates for the control points:
> 86, 143, 147
> 135, 152, 163
>
> Cheers, Clara
>
> ----- Ursprüngliche Mail -----
> Von: "ckuehn" <cku...@cbs.mpg.de>
> An: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
> Gesendet: Dienstag, 30. Juni 2015 11:39:40
> Betreff: Re: [Freesurfer] too much white matter
>
> Hi Bruce,
> thanks for your reply. As far as I can tell the cps are in the WM. I'd be 
> grateful if you could take a closer look, though. You can download the 
> dataset here:
> https://bigmail.cbs.mpg.de/i/2581030103b072173ff426e67d298cf4.zip
>
> Cheers, Clara
>
> ----- Ursprüngliche Mail -----
> Von: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
> An: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
> Gesendet: Montag, 29. Juni 2015 18:07:28
> Betreff: Re: [Freesurfer] too much white matter
>
> Hi Clara
>
> are you sure you put the control points in the interior of the WM? If you
> want to upload the subject we will take a look
>
> cheers
> Bruce
> On Mon, 29 Jun 2015, Clara
> Kühn wrote:
>
>> Dear Freesurfer experts,
>>
>> I've had this problem now a couple of times: after setting a few (in this 
>> case 2) control points and rerunning the recon-all process with the -cp flag 
>> I get huge areas of white matter including the subcortical areas and lots of 
>> the cortical ribbon. See attached picture.
>> Could you explain how this happens because the logfile says it ran without 
>> error. In these cases I've deleted the whole thing and preprocessed the scan 
>> from scratch. I was wondering if there's a better way to deal with this like 
>> going a step back if that's possible.
>>
>> Cheers,
>> Clara Kühn
>>
>>
>>
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