Hi Jane we don't really see much blurring of folding patterns with the high-dimensional spherical warp so you might as well use them all (although there might be issues with memory - perhaps Doug can comment if this is still true).
cheers Bruce On Wed, 6 May 2015, Jane Garrison wrote: > > Hi, > > I have a question about the utility of the make_average_subject command. > > I have a schizophrenia study with 115 subjects and am worried about using the > Freesurfer average brain, given that scz patients have distinct morphological > aspects to their brains. I am therefore considering making an average brain > from my subjects, but have read some old posts cautioning against this, since > an average brain taken across a large number may be too indistinct to be of > value. > > Is there a recommendation on this - should I produce an average across all my > subjects, or should I maybe use a small (20?) sample of my subject brains to > create an average? > > Thanks so much > > Jane. > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.