Dear Freesurfer Mailing List,

I sent the below email last week and have not yet recieved a reply. Does anyone have any ideas about the problem I am experiencing?

Kind regards,

Bronwyn Overs
Research Assistant

Neuroscience Research Australia

Neuroscience Research Australia
Margarete Ainsworth Building
Barker Street Randwick Sydney NSW 2031 Australia
*M* 0411 308 769 *T* +61 2 9399 1883 *F* +61 2 9399 1265

neura.edu.au <http://neura.edu.au>

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On 7/04/2015 11:48 am, Bronwyn Overs wrote:
Dear Freesurfer Mailing List,

I have just run a GLM analysis using mri_glmfit with area as the measure of interest. For each of my significant contrasts, I extracted the mean area for each subjects from the corresponding cache.th13.abs.y.ocn.dat file. I then plotted these values to examine the nature of the interaction. In doing so I identified three individuals who had extreme mean area values (up to 11 sd from the average of the mean area) for many of the significant clusters. For each of these individuals I cannot see any problems with the freesurfer .mgz files or the cortical segmentation.

So my questions are:
1. Are extreme mean values for significant clusters in GLM a problem? If so, do you have any idea what could be causing these values if the scans appear to be well segmented? 2. If the significant clusters are calculated at a group level, how are the individual mean values (in cache.th13.abs.y.ocn.dat) generated?
--

Kind regards,

Bronwyn Overs
Research Assistant

Neuroscience Research Australia

Neuroscience Research Australia
Margarete Ainsworth Building
Barker Street Randwick Sydney NSW 2031 Australia
*M* 0411 308 769 *T* +61 2 9399 1883 *F* +61 2 9399 1265

neura.edu.au <http://neura.edu.au>

Follow @neuraustralia on twitter <https://twitter.com/neuraustralia>Follow NeuRA on facebook <https://www.facebook.com/NeuroscienceResearchAustralia>



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