Try demeaning each covariate. Do so with respect to the mean across all subjects and not within group. doug
On 01/15/2015 08:02 AM, 이현아 wrote: > /Hello/ > /I’m trying to do an group analysis using mir_glmfit but I met this error./ > ERROR: matrix is ill-conditioned or badly scaled, condno = 165279 > > 1. my command line was > > mri_glmfit --y lh.age_edu.thickness.10b.mgh --fsgd age_edu.fsgd --C > C_age.edu.mtx --surf fsaverage lh --cortex --glmdir lh.age_edu.glmdir > > 2. I attached the fsgd file, which was made in edit. It contains 1 > class (2 levels) and 2 variables (age & education) > > 3. contrast is ‘-1 1 0 0 0 0’ > 4. design matrix is like below > Design matrix ------------------ > 1.000 0.000 74.000 0.000 14.000 0.000; > 1.000 0.000 70.000 0.000 12.000 0.000; > 1.000 0.000 73.000 0.000 6.000 0.000; > 1.000 0.000 84.000 0.000 15.000 0.000; > 0.000 1.000 0.000 60.000 0.000 12.000; > 0.000 1.000 0.000 59.000 0.000 12.000; > 0.000 1.000 0.000 63.000 0.000 9.000; > 0.000 1.000 0.000 60.000 0.000 12.000; > -------------------------------- > ERROR: matrix is ill-conditioned or badly scaled, condno = 164365 > > Possible problem with experimental design: > Check for duplicate entries and/or lack of range of > continuous variables within a class. > If you seek help with this problem, make sure to send: > 1. Your command line: > mri_glmfit --y lh.age_edu.thickness.10b.mgh --fsgd age_edu.fsgd > --C C_age.edu.mtx --surf fsaverage lh --cortex --glmdir lh.age_edu.glmdir > 2. The FSGD file (if using one) > 3. And the design matrix above > > > > thanks, > > H.A. LEE > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
