It is more straightforward if you use -log10(p). If you want to do an 
unsigned test, then run it twice, once with pos and once with neg, then 
multiply the resulting cluster-wise p-values by 2.
doug

On 10/21/2014 02:11 AM, Joo Tan wrote:
>
> Hi
>
>
> I have a few questions regarding the use of “mri_volcluster” for 
> clusterwise thresholding. Essentially, we have a volume of pvalues 
> obtained from a two tailed t-test comparing beta values from condition 
> A vs condition B.
>
> When I ran this command:
>
> mri_volcluster --intransformedP.nii --sum cwthres_sum.txt --sign abs 
> --fwhm 6--mask avgmas.nii --cwpvalthresh 0.05--thmin 2.3 --cwsig 
> cwthresclusters.cwsig.nii
>
> I got this error message:
>
> ERROR: you must specify a pos or neg sign with --fwhm
>
> Input was –log10(p-value)
>
> Thmin was –log10(primary p threshold)
>
> Is there a way to perform clusterwise thresholding on results from two 
> tailed tests? Is it essential to use –log10(p) values as input? Can I 
> use raw t-values or any other values as input and thmin instead?
>
> Finally, are there any papers/references which this command is based on?
>
>
> Many thanks!
>
>
> _______________________________________________
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> Freesurfer@nmr.mgh.harvard.edu
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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Fax: 617-726-7422

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