Hi Domenico

can you send us the image? And what do you mean by "the sign of the 
image"? Is it T1-weighted? Is white matter brighter than gray matter? If 
so, then try running it through recon-all.

cheers
Bruce
On Fri, 3 Oct 2014, Domenico 
wrote:

> Dear all,
> I have a set of 3D true IR volumes acquired on a Siemens Avanto Scanner
> 1.5T.
> The GM/WM contrast is very good and the images look better (from a
> neuroradiological point of you) than the classical 3D T1 we usually acquire.
> The sign of the images (that in this sequence could be <0) could be adjusted
> (for example using Matlab) so to maintain the intensity ratio between the
> structures.
> 
> Do you think I could use them for a Freesurfer analysis? Unfortunately the
> subjects were acquired some time ago, before starting to use FreeSurfer and
> only this 3DT1 sequence was acquired.
> 
> Thank you,
> 
> Kind regards,
> 
> Domenico
> 
>
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