Hi Alfred,
using FS longitudinal will increase reliability of measurements and is
always the right tool for longitudinal studies. However, images will
look consistently different across the two scanners. You will never know
if the differences that you find are caused by the scanner change or by
changing anatomy. It's really worse than 'far less than ideal'.
Best, Martin
On 06/22/2014 02:01 PM, Alfred Ochs wrote:
Colleagues,
We are preparing to perform longitudinal pilot studies a group of
subjects and controls under far less than ideal conditions.The initial
MRI scans were done clinically on a 1.5T Siemens scanner using the
ADNI Siemens scanning protocol.The follow-up scans need to be done on
a 3.0T Phillips (research, i.e., gratis) scanner using the ADNI
Phillips protocol.Am I correct in assuming that the FreeSurfer
longitudinal pipeline will somewhat iron out the inherent segmentation
& parcellation differences between MRIs taken on these two machines?
Thank you, Alfred Ochs
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--
Martin Reuter, Ph.D.
Instructor in Neurology
Harvard Medical School
Assistant in Neuroscience
Dept. of Radiology, Massachusetts General Hospital
Dept. of Neurology, Massachusetts General Hospital
Research Affiliate
Computer Science and Artificial Intelligence Lab,
Dept. of Electrical Engineering and Computer Science,
Massachusetts Institute of Technology
A.A.Martinos Center for Biomedical Imaging
149 Thirteenth Street, Suite 2301
Charlestown, MA 02129
Phone: +1-617-724-5652
Email:
mreu...@nmr.mgh.harvard.edu
reu...@mit.edu
Web : http://reuter.mit.edu
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