Hello Everyone,
could someone please give us an advice about which method you consider
is the best for our study ?
we have two groups with MRI at Time 1. Each group received medication.
After this we performed another MRI at Time 2 after 2 weeks.
The best method for this study is a longitudinal one or a
cross-sectional GLM ?
We consider that the distance between the time points is too small, and
the longitudinal method is not the best choice. Hence,this study should
be treated as a cross-sectional one. In this case we think about
performing a simple GLM with the contrasts:
0.5 0.5 0.5 0.5
or 1 -1 -1 1
for the groups:
1) grp 1 time 1
2) grp 1 time 2
3) grp 2 time 1
4) grp 2 time 2
we are searching to see whether medication had any impact on the
cortical morphology in each group and between the groups.
Thank you !
Best regards,
Alex.
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