The partial volume correction is done based on the intensity and label 
of the surrounding voxels. By using aparc+aseg you change the label of 
the surrounding structures and it changes the PV correction. Use 
aseg.mgz and not aparc+aseg
doug

On 05/09/2014 05:27 AM, Schreiber, Stefanie wrote:
> Dear all,
>
> For the evaluation of the subcortical volumes we executed ‘mri_segstats’ on 
> ‘aseg.mgz’ and for comparison on ‘aparc+aseg.mgz’ in a number of individuals. 
> Apparently the volume of subcortical structures, like the hippocampus, is 
> calculated as the same values if calculated (without partial volume 
> correction) from ‘aseg.mgz’ and ‘aparc+aseg.mgz’.
> However, when partial volume correction is applied, the resulting values for 
> e.g. hippocampal volumes differ between the ‘mri_segstats’ calculation for 
> ‘aseg.mgz’ and ‘aparc+aseg.mgz’. How could those differences resulting from 
> the partial volume correction in these cases be explained?
>
> The command used to calculate the subcortical volumes with partial volume 
> correction was:
> mri_segstats --seg ./mri/aparc+aseg.mgz --ctab 
> $FREESURFER_HOME/FreeSurferColorLUT.txt --excludeid 0 --sum 
> ./stats/my.test.stats --pv ./mri/norm.mgz
>
> Previously we have been using the subcortical volumes from ‘aseg.stats’, 
> which, as I understand it, is generated by recon-all from ‘aseg.mgz’ via 
> ‘mri_segstats’ (with partial volume correction).  From your experience, would 
> it be also valid to use subcortical volumes generated by applying 
> ‘mri_segstats’ (with partial volume correction) on ‘aparc+aseg.mgz’, even 
> though the resulting values might differ from the values in aseg.stats?
>
> Thank you very much in advance,
>
> Steffi Schreiber
>
>
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>
>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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Fax: 617-726-7422

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