Thanx Bruce,

I will try out your suggestion and let you know. I think I will get a good 
estimate of the degree of metric distortions, because I have a lot of subjects 
tested ;-)

If this will not work, or the distortions are to big, I will make use of the 
Spline Tool in Freeview manually drawing a line within the cortical ribbon 
between the peak voxels, whereby benefitting from the reconstructed surface 
brain with superimposed EPI (with post inflation smoothed EPI data) for visual 
comparison (to benefit from the SBR versus VBR information, to avoid the 
problem of guessing if an activated cluster belongs to Gyrus A or B when the 
Cluster is spread along two attached gyri). Maybe I can also make use of the 
coordinate transormations RAS <-->sphere

Greetz,

Christopher
 
________________________________________
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[freesurfer-boun...@nmr.mgh.harvard.edu]&quot; im Auftrag von &quot;Bruce 
Fischl [fis...@nmr.mgh.harvard.edu]
Gesendet: Montag, 12. Mai 2014 15:46
An: Freesurfer support list
Betreff: Re: [Freesurfer] distance comparisons across subjects in fsaverage 
group sphere

Hi Christopher

the spherical mapping usually has on the order of 17-20% distortion in
distances, and the registration is probably significantly more. I'm not
entirely sure what are trying to do, but you can measure the difference in
great circle length between the sphere and sphere.reg to get an idea of how
much additional distortion is induced by the registration

cheers
Bruce



On Mon, 12 May 2014, Milde, Christopher wrote:

>
> Dear Freesurfers,
>
>
>
> In Fischl et al. 1999 it is highlighted, that the topological structure of 
> the original
> surface is preserved in the spherical space and due to the nature of a 
> sphere, computations
> (distance, area) measures are easy to make.
>
>
>
> My question now, concerns the comparability of distance measures between 
> subjects in the
> group fsaverage sphere. My aim is to compare distances between peak voxels 
> coordinates of
> two study populations, to figure out if a systematic difference exist between 
> the peak voxel
> distances of the two study populations.
>
>
>
> Can I compare the distances between peak voxels (vertices) between different 
> subjects based
> on the fsaverage group sphere? So, is the comparability of distances between 
> vertexes of
> individually spheres preserved in group fsaverage space?
>
>
>
> Ps: I know that the distances in spherical space are not Euclidian but still 
> geodesic
>
>
>
>
>
> Best wishes and thanks in advance,
>
>
>
>
>
> Christopher Milde, M.Sc. Biol.
>
> Institute for Cognitive and Clinical Neuroscience
>
> Central Institute of Mental Health Square J 5
>
> 68159 Mannheim, Germany
>
>
>
>
>
> Christopher Milde, M.Sc. Biol.
>
> Institute for Cognitive and Clinical Neuroscience
>
> Central Institute of Mental Health Square J 5
>
> 68159 Mannheim, Germany
>
>
>
> Phone:                  +49-621-1703-6313
>
> E-mail:                  christopher.mi...@zi-mannheim.de
>
> Homepage:        http://www.zi-mannheim.de/
>
> Office:                  Forschungs- und Verwaltungsgebäude, Room 230
>
>
>
>
>

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