From the output it looks like the func-anat registration is off, 
probably because of the partial FoV is causing the FSL registration used 
to init BBR to be off (often happens with a partial FoV). Were the 
anatomical and functional acquired at the same time? If so, then you'll 
have to bypass reg-feat2anat to create the registration.

Unless you use --overwrite-exf2std, the exf2anat will not affect the exf2std

doug


On 02/02/2014 05:59 PM, Mariam Sood wrote:
> Hello Doug,
> Thank you for your reply. I tried to investigate it further and would be 
> grateful for your advice. While the reg-feat2anat registration (default FSL 
> option) looks way off, the FEAT generated registration, both 
> functional-anatomical and functional-standard look fine. I have used 
> brainmask.nii as the anatomical in the registration tab of FEAT (with ‘bbr’ 
> option selected for functional-standard registration and linear 12DOF for 
> registration to standard). This is a partial FOV image and the determinant of 
> functional & anatomical have opposite signs. Attached, please find my 
> reg-feat2anat log file.
>
> Also from your reply, what I understood is that exf2std.reg.dat is generated 
> by FSL routines. Won’t exf2anat registration play any part in this?
>
> I also have a T1-weighted alignment scan acquired with the same orientation 
> and slice-block centre as the functional data. Is it possible to make use of 
> this to get better registration should other methods fail?
>
> Many thanks,
> Mariam.
>
>
>
>
>
> On 30 Jan 2014, at 17:43, Douglas N Greve <gr...@nmr.mgh.harvard.edu> wrote:
>
>> The second warning you don't need to worry about. I should change that
>> to not be a warning. reg-feat2anat is only registering the functional
>> and anatomical. If the registration to mni152 does not look good, then
>> that is an FSL issue
>> doug
>>
>> On 01/30/2014 11:06 AM, Mariam Sood wrote:
>>> Hello,
>>>
>>> I am running reg-feat2anat and facing some problems.
>>>
>>> First I ran the command in its default mode using FSL initialisation
>>> /reg-feat2anat --feat featdir.feat --subject s. /That gave me a bad
>>> registration. There is a warning coming up
>>> ///WARNING: //initial G-W contrast is negative, but expecting positive./
>>> /  If the mov data has a T1 contrast, re-run with --T1/
>>>
>>> Next I tried the command using -spm option. The within-subject
>>> registration (anat2exf) looks good, but the registration to the
>>> standard does not look that good, although not as bad as with -fsl
>>> option.
>>>
>>> The structural and the functional are using different conventions
>>> (structural is in radiological convention, whereas functional is
>>> neurological). I presume the determinants are associated with this and
>>> they have opposite signs. The orientations are also different.
>>> Additionally in both the log files (one with -fsl option and -spm
>>> option), I get another warning /WARNING:: Flipping Left/Right
>>> orientation (as det < 0). /Not sure whether this warning is something
>>> I should worry about.
>>>
>>> Much appreciate your help.
>>>
>>> Many thanks,
>>> Mariam.
>>>
>>>
>>>
>>>
>>> _______________________________________________
>>> Freesurfer mailing list
>>> Freesurfer@nmr.mgh.harvard.edu
>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>> -- 
>> Douglas N. Greve, Ph.D.
>> MGH-NMR Center
>> gr...@nmr.mgh.harvard.edu
>> Phone Number: 617-724-2358
>> Fax: 617-726-7422
>>
>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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