There is still no difference between that and doing a regular thickness 
study with two groups. Were are you getting stuck?
doug


On 01/17/2014 12:35 PM, krista kelly wrote:
> Hi Doug,
>
> Sorry I should have specified BETWEEN groups analyses. I have two 
> groups (control, patient) and I wanted to see if the hemisphere 
> asymmetries (or laterality indices) differed between groups. Is there 
> a way to do that?
>
> Thanks for all you help!
> Krista
>
>
> On Mon, Jan 13, 2014 at 6:25 PM, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>
>     yes, it is just like a "normal" group analysis. You create a stack
>     of LI
>     maps, one for each subject, create an FSGD file, run mri_glmfit, then
>     mri_glmfit-sim.
>
>     doug
>
>
>
>     On 01/13/2014 06:22 PM, krista kelly wrote:
>     >
>     > Just wanted to repost this in case anyone else can give some advice.
>     > Thanks!
>     >
>     > Is there any way to analyze group differences with xhemi? I can get
>     > the laterality indices per group, but I'd like to do a whole brain
>     > analyses looking at group differences in laterality indices.
>     >
>     > Thanks,
>     > Krista
>     >
>     >
>     > On Tue, Dec 10, 2013 at 2:01 PM, Douglas N Greve
>     > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
>     >
>     >
>     >     Yes, use the cache files. When "--cache" is used, the
>     csdbase="cache"
>     >
>     >     On 12/10/2013 12:20 PM, krista kelly wrote:
>     >     > Hi again,
>     >     >
>     >     > I've looked into mri_glmfit-sim --help to figure out which
>     files I
>     >     > could overlay in tkurfer after correcting for multiple
>     comparisons
>     >     > using the instructions for xhemi on the freesurfer wiki.
>     >     However, I do
>     >     > not see any of these files (csd.base...) in the glmdir/osgm
>     >     folder. I
>     >     > only see ones that begin with cache..... Are these the files I
>     >     should
>     >     > be overlaying? Or should I be using different commands for my
>     >     analyses?
>     >     >
>     >     > here is the command line I used:
>     >     >
>     >     > mri_glmfit-sim --glmdir glm.lh.lh-rh.area.pial.sm05 \
>     >     > --cwpvalthresh .5 --cache 2 abs
>     >     >
>     >     > Prior to mri_glmfit, I conducted the "create a stack of
>     subjects"
>     >     > using paired-diff-norm in place of paired-diff
>     >     >
>     >     > Ultimately, I want to look at hemisphere asymmetries
>     (preferably in
>     >     > terms of laterality indices) in two different groups
>     separately.
>     >     >
>     >     > I would also like to see if laterality indices differ between
>     >     groups.
>     >     > Is this possible?
>     >     >
>     >     > Thanks!
>     >     > Krista
>     >     >
>     >     >
>     >     > On Mon, Dec 9, 2013 at 4:00 PM, krista kelly
>     >     <krista.kell...@gmail.com <mailto:krista.kell...@gmail.com>
>     <mailto:krista.kell...@gmail.com <mailto:krista.kell...@gmail.com>>
>     >     > <mailto:krista.kell...@gmail.com
>     <mailto:krista.kell...@gmail.com>
>     >     <mailto:krista.kell...@gmail.com
>     <mailto:krista.kell...@gmail.com>>>> wrote:
>     >     >
>     >     >     Great Thanks!
>     >     >
>     >     >
>     >     >
>     >     >
>     >     >     On Mon, Dec 9, 2013 at 11:57 AM, Douglas N Greve
>     >     >     <gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>
>     >     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>
>     >     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>
>     >     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>>> wrote:
>     >     >
>     >     >
>     >     >         On 12/09/2013 11:53 AM, krista kelly wrote:
>     >     >         > Thanks Doug! I'll try that instead.
>     >     >         >
>     >     >         > Also, do you or anyone else happen to have the
>     answers
>     >     to my
>     >     >         other
>     >     >         > questions (reposted below):
>     >     >         >
>     >     >         > 1) When viewing the results in tksurfer, which color
>     >     >         represents "left
>     >     >         > hemisphere is larger" and which represents "right
>     >     hemisphere
>     >     >         is larger"?
>     >     >         If you are just doing a simple interhemispheric
>     >     difference, then
>     >     >         yellow/red will be left>right and blue left<right
>     >     >         >
>     >     >         > 2) I have no idea how to view the results in
>     tksurfer
>     >     AFTER
>     >     >         performing
>     >     >         > the step of correcting for multiple comparisons. Any
>     >     >         suggestions?
>     >     >
>     >     >         If you run mri_glmfit-sim with --help you will see
>     a list of
>     >     >         output
>     >     >         files with descriptions for each. Choose the one you
>     >     want and run
>     >     >         tksurfer on it (eg, tksurfer fsaverage_sym lh inflated
>     >     -aparc
>     >     >         -overlay
>     >     >         csdbase.sig.cluster.mgh )
>     >     >
>     >     >         doug
>     >     >
>     >     >         >
>     >     >         > Thanks!
>     >     >         > Krista
>     >     >         >
>     >     >         >
>     >     >         >
>     >     >         >
>     >     >         > On Mon, Dec 9, 2013 at 11:09 AM, Douglas N Greve
>     >     >         > <gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>
>     >     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>
>     >     >         <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>
>     >     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>>
>     >     >         <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>
>     >     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>
>     >     >         <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>
>     >     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>>>> wrote:
>     >     >         >
>     >     >         >     Run mris_preproc with --paired-diff-norm which
>     >     will then
>     >     >         compute
>     >     >         >        LI = (L-R)/(.5*(L+R))
>     >     >         >     Note that some people use
>     >     >         >        LI = (L-R)/(L+R)
>     >     >         >     If that is what you want, then divide the
>     mris_preproc
>     >     >         result by 2
>     >     >         >
>     >     >         >     doug
>     >     >         >
>     >     >         >     On 12/08/2013 08:45 PM, krista kelly wrote:
>     >     >         >     > Hello,
>     >     >         >     >
>     >     >         >     > I'm analysing interhemispheric differences
>     using
>     >     >         xhemi. I have
>     >     >         >     > followed the instructions on the webpage
>     with no
>     >     >         problems. I do
>     >     >         >     have a
>     >     >         >     > few questions though.
>     >     >         >     >
>     >     >         >     > 1) When viewing the results in tksurfer,
>     which color
>     >     >         represents
>     >     >         >     "left
>     >     >         >     > hemisphere is larger" and which represents
>     "right
>     >     >         hemisphere is
>     >     >         >     larger"?
>     >     >         >     >
>     >     >         >     > 2) I have no idea how to view the results in
>     >     tksurfer
>     >     >         AFTER
>     >     >         >     performing
>     >     >         >     > the step of correcting for multiple
>     comparisons. Any
>     >     >         suggestions?
>     >     >         >     >
>     >     >         >     > 3) I've noticed from the archives that some
>     >     people are
>     >     >         performing
>     >     >         >     > laterality indices. How would I calculate
>     laterality
>     >     >         indices?
>     >     >         >     >
>     >     >         >     > Thanks!
>     >     >         >     > Krista
>     >     >         >     >
>     >     >         >     >
>     >     >         >     >
>     >     >         >     >
>     >     >         >     >
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>     >     >         >
>     >     >         >     --
>     >     >         >     Douglas N. Greve, Ph.D.
>     >     >         >     MGH-NMR Center
>     >     >         > gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>
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>     >     >         --
>     >     >         Douglas N. Greve, Ph.D.
>     >     >         MGH-NMR Center
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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