Hi Doug,

Sorry I should have specified BETWEEN groups analyses. I have two groups
(control, patient) and I wanted to see if the hemisphere asymmetries (or
laterality indices) differed between groups. Is there a way to do that?

Thanks for all you help!
Krista


On Mon, Jan 13, 2014 at 6:25 PM, Douglas N Greve
<gr...@nmr.mgh.harvard.edu>wrote:

>
> yes, it is just like a "normal" group analysis. You create a stack of LI
> maps, one for each subject, create an FSGD file, run mri_glmfit, then
> mri_glmfit-sim.
>
> doug
>
>
>
> On 01/13/2014 06:22 PM, krista kelly wrote:
> >
> > Just wanted to repost this in case anyone else can give some advice.
> > Thanks!
> >
> > Is there any way to analyze group differences with xhemi? I can get
> > the laterality indices per group, but I'd like to do a whole brain
> > analyses looking at group differences in laterality indices.
> >
> > Thanks,
> > Krista
> >
> >
> > On Tue, Dec 10, 2013 at 2:01 PM, Douglas N Greve
> > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
> >
> >
> >     Yes, use the cache files. When "--cache" is used, the csdbase="cache"
> >
> >     On 12/10/2013 12:20 PM, krista kelly wrote:
> >     > Hi again,
> >     >
> >     > I've looked into mri_glmfit-sim --help to figure out which files I
> >     > could overlay in tkurfer after correcting for multiple comparisons
> >     > using the instructions for xhemi on the freesurfer wiki.
> >     However, I do
> >     > not see any of these files (csd.base...) in the glmdir/osgm
> >     folder. I
> >     > only see ones that begin with cache..... Are these the files I
> >     should
> >     > be overlaying? Or should I be using different commands for my
> >     analyses?
> >     >
> >     > here is the command line I used:
> >     >
> >     > mri_glmfit-sim --glmdir glm.lh.lh-rh.area.pial.sm05 \
> >     > --cwpvalthresh .5 --cache 2 abs
> >     >
> >     > Prior to mri_glmfit, I conducted the "create a stack of subjects"
> >     > using paired-diff-norm in place of paired-diff
> >     >
> >     > Ultimately, I want to look at hemisphere asymmetries (preferably in
> >     > terms of laterality indices) in two different groups separately.
> >     >
> >     > I would also like to see if laterality indices differ between
> >     groups.
> >     > Is this possible?
> >     >
> >     > Thanks!
> >     > Krista
> >     >
> >     >
> >     > On Mon, Dec 9, 2013 at 4:00 PM, krista kelly
> >     <krista.kell...@gmail.com <mailto:krista.kell...@gmail.com>
> >     > <mailto:krista.kell...@gmail.com
> >     <mailto:krista.kell...@gmail.com>>> wrote:
> >     >
> >     >     Great Thanks!
> >     >
> >     >
> >     >
> >     >
> >     >     On Mon, Dec 9, 2013 at 11:57 AM, Douglas N Greve
> >     >     <gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>
> >     <mailto:gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
> >     >
> >     >
> >     >         On 12/09/2013 11:53 AM, krista kelly wrote:
> >     >         > Thanks Doug! I'll try that instead.
> >     >         >
> >     >         > Also, do you or anyone else happen to have the answers
> >     to my
> >     >         other
> >     >         > questions (reposted below):
> >     >         >
> >     >         > 1) When viewing the results in tksurfer, which color
> >     >         represents "left
> >     >         > hemisphere is larger" and which represents "right
> >     hemisphere
> >     >         is larger"?
> >     >         If you are just doing a simple interhemispheric
> >     difference, then
> >     >         yellow/red will be left>right and blue left<right
> >     >         >
> >     >         > 2) I have no idea how to view the results in tksurfer
> >     AFTER
> >     >         performing
> >     >         > the step of correcting for multiple comparisons. Any
> >     >         suggestions?
> >     >
> >     >         If you run mri_glmfit-sim with --help you will see a list
> of
> >     >         output
> >     >         files with descriptions for each. Choose the one you
> >     want and run
> >     >         tksurfer on it (eg, tksurfer fsaverage_sym lh inflated
> >     -aparc
> >     >         -overlay
> >     >         csdbase.sig.cluster.mgh )
> >     >
> >     >         doug
> >     >
> >     >         >
> >     >         > Thanks!
> >     >         > Krista
> >     >         >
> >     >         >
> >     >         >
> >     >         >
> >     >         > On Mon, Dec 9, 2013 at 11:09 AM, Douglas N Greve
> >     >         > <gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>
> >     >         <mailto:gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>>
> >     >         <mailto:gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>
> >     >         <mailto:gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>>>> wrote:
> >     >         >
> >     >         >     Run mris_preproc with --paired-diff-norm which
> >     will then
> >     >         compute
> >     >         >        LI = (L-R)/(.5*(L+R))
> >     >         >     Note that some people use
> >     >         >        LI = (L-R)/(L+R)
> >     >         >     If that is what you want, then divide the
> mris_preproc
> >     >         result by 2
> >     >         >
> >     >         >     doug
> >     >         >
> >     >         >     On 12/08/2013 08:45 PM, krista kelly wrote:
> >     >         >     > Hello,
> >     >         >     >
> >     >         >     > I'm analysing interhemispheric differences using
> >     >         xhemi. I have
> >     >         >     > followed the instructions on the webpage with no
> >     >         problems. I do
> >     >         >     have a
> >     >         >     > few questions though.
> >     >         >     >
> >     >         >     > 1) When viewing the results in tksurfer, which
> color
> >     >         represents
> >     >         >     "left
> >     >         >     > hemisphere is larger" and which represents "right
> >     >         hemisphere is
> >     >         >     larger"?
> >     >         >     >
> >     >         >     > 2) I have no idea how to view the results in
> >     tksurfer
> >     >         AFTER
> >     >         >     performing
> >     >         >     > the step of correcting for multiple comparisons.
> Any
> >     >         suggestions?
> >     >         >     >
> >     >         >     > 3) I've noticed from the archives that some
> >     people are
> >     >         performing
> >     >         >     > laterality indices. How would I calculate
> laterality
> >     >         indices?
> >     >         >     >
> >     >         >     > Thanks!
> >     >         >     > Krista
> >     >         >     >
> >     >         >     >
> >     >         >     >
> >     >         >     >
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> >     >         >
> >     >         >     --
> >     >         >     Douglas N. Greve, Ph.D.
> >     >         >     MGH-NMR Center
> >     >         > gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>
> >     <mailto:gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu
> >>
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> >     >         MGH-NMR Center
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> >     MGH-NMR Center
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