Freesurfer experts, I am interested in converting functional ROIs defined by the Greicius lab ( http://findlab.stanford.edu/functional_ROIs.html) into individual subject space. Originally I had converted the fROIs from an FSL-based MNI152 to Freesurfer-based MNI305 space. To do this I used this command (in this case for the precuneus network fROI):
*mri_label2vol \* *--seg Precuneus.nii.gz \* *--reg $FREESURFER_HOME/average/mni152.register.dat \* *--invertmtx --o Precuneus_FS.nii.gz \* *--temp $FREESURFER_HOME/subjects/fsaverage/mri/mni305.cor.mgz* *The output file's information, provided by 3dinfo, is as follows:* Template Space: ORIG Dataset Type: Anat Bucket (-abuc) Byte Order: LSB_FIRST {assumed} [this CPU native = LSB_FIRST] Storage Mode: NIFTI Storage Space: 67,108,864 (67 million [mega]) bytes Geometry String: "MATRIX(1,0,0,-128,0,0,-1,128,0,-1,0,128):256,256,256" Data Axes Tilt: Plumb Data Axes Orientation: first (x) = Right-to-Left second (y) = Superior-to-Inferior third (z) = Posterior-to-Anterior [-orient RSP] R-to-L extent: -128.000 [R] -to- 127.000 [L] -step- 1.000 mm [256 voxels] A-to-P extent: -127.000 [A] -to- 128.000 [P] -step- 1.000 mm [256 voxels] I-to-S extent: -127.000 [I] -to- 128.000 [S] -step- 1.000 mm [256 voxels] Number of values stored at each pixel = 1 -- At sub-brick #0 '?' datum type is float I would like to take the output of this command and convert it to an individual subject's space. However, I'm not really sure how to proceed. Originally I thought the above command, in using the mni305.cor.mgz file in fsaverage's mri folder, would put the output file into fsaverage's space. I could then, I figured, use some other commands I have for moving things in fsaverage space to individual subject space. Unfortunately, when I try to load the above output file into tkmedit for fsaverage as an aux volume it's essentially off screen (i.e. not in the brain). Obviously the output file is not in fsaverage space, per se. Any thoughts on how to proceed? Thanks, Paul -- Paul Beach DO/PhD candidate - Year VI Michigan State University - College of Osteopathic Medicine - Neuroscience Program - Bozoki Lab: Neurology/Radiology
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