Got you. I will check out ribbon and read more about mri_vol2surf. Thanks for 
your help!
Yue

> Date: Fri, 1 Nov 2013 12:16:48 -0400
> From: fis...@nmr.mgh.harvard.edu
> To: moonblue...@hotmail.com
> CC: freesurfer@nmr.mgh.harvard.edu
> Subject: RE: [Freesurfer] How to generate histograms of intensities in one 
> anatomical region?
> 
> the surfaces can be used to sample in many different ways using options to 
> mri_vol2surf. For example you could average over the ribbon then display 
> the histogram of that. For subcortical structures the surfaces don't make 
> sense, so you are better off just doing it in matlab cheers Bruce
> 
> 
> On Fri, 
> 1 Nov 2013, ?? wrote:
> 
> > Hi Bruce,
> > Thanks for responding so quickly.
> > 
> > Sorry I probably don't describe my question clearly and my examples are bad.
> > This is really new to me. So please correct me if I say something wrong. Let
> > me explain again. Hopefully it will make some sense. 
> > 
> > What I want to do is first to segment out different cortical and subcorical
> > regions(like frontal cortex, occipital cortex, posterior cingulate cortex,
> > putamen etc.) and then generate histograms from these regions separately.
> > The surfaces give me the histograms that only include the intensities on the
> > edges of the regions, right? I am wondering if I can generate histograms
> > from the area of one cortical region not just the boundaries. Thanks!
> > 
> > 
> > Best,
> > Yue
> > 
> > 
> > > Date: Fri, 1 Nov 2013 11:12:46 -0400
> > > From: fis...@nmr.mgh.harvard.edu
> > > To: moonblue...@hotmail.com
> > > CC: freesurfer@nmr.mgh.harvard.edu
> > > Subject: RE: [Freesurfer] How to generate histograms of intensities in one
> > anatomical region?
> > >
> > > Hi Yue
> > >
> > > tksurfer will only display cortical histograms. For subcortical regions
> > > you are probably best off using something like matlab (which would be
> > > pretty trivial)
> > >
> > > cheers
> > > Bruce
> > > On Fri, 1 Nov 2013, ?? wrote:
> > >
> > > >
> > > > Hi Bruce,
> > > > Thanks for the information. The surface works for me. These histograms
> > > > generated from the surfaces, if I understand correctly, are based on the
> > > > intensities along the boundaries of one region. Can I also generate
> > > > histograms including the whole region? Like Pick putamen or caudate and
> > > > generate histograms and statistic summaries based on all the pixels in
> > those
> > > > regions. Or can I generate binary masks of putamen or caudate from the
> > > > labels then I can apply those masks and generate histograms in other
> > > > softwares? Thanks a lot!
> > > >
> > > >
> > > > Best,
> > > > Yue
> > > > > Date: Fri, 1 Nov 2013 08:45:35 -0400
> > > > > From: fis...@nmr.mgh.harvard.edu
> > > > > To: moonblue...@hotmail.com
> > > > > CC: freesurfer@nmr.mgh.harvard.edu
> > > > > Subject: Re: [Freesurfer] How to generate histograms of intensities in
> > one
> > > > anatomical region?
> > > > >
> > > > > Hi Yue
> > > > >
> > > > > if you sample them on to the surface with mri_vol2surf you can use the
> > > > > overlay histogram facility in tksurfer to do what you want. You can
> > also
> > > > > use mask_label to remove values outside of an ROI if that is what you
> > are
> > > > > interested in.
> > > > >
> > > > > cheers
> > > > > Bruce
> > > > > On Fri, 1 Nov 2013, ?? wrote:
> > > > >
> > > > > > Hi All,
> > > > > > I have T1-weighted MPRAGE images and I run recon-all to generate
> > > > surfaces
> > > > > > and labels in freesurfer. Then I would like to do statistical
> > analysis
> > > > in
> > > > > > the regions I am interested in. For example, I would like to
> > generate a
> > > > > > histogram of intensities in frontal cortex or in occipital. I can
> > > > display
> > > > > > these regions in different color in freeview based on the look-up
> > table
> > > > but
> > > > > > I don't know how to use them to generate histograms in freesurfer or
> > > > create
> > > > > > binary masks then I can do the analysis with these masks in matlab. 
> > > > > >
> > > > > > I use freesurfer to do this because I see these beautiful color
> > > > > > segmentations. It would be really painful to manually create
> > regional
> > > > masks
> > > > > > for a group study. I am new to freesurfer and I really appreciate if
> > > > someone
> > > > > > can point out a direction. 
> > > > > >
> > > > > > Thanks!
> > > > > >
> > > > > >
> > > > > > Best,
> > > > > > Yue
> > > > > >
> > > > > >
> > > > >
> > > > >
> > > > > The information in this e-mail is intended only for the person to whom
> > it
> > > > is
> > > > > addressed. If you believe this e-mail was sent to you in error and the
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> > > > HelpLine at
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> > > > > but does not contain patient information, please contact the sender
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> > > >
> > > >
> > 
> >
                                          
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