Why is a small # a problem? It simply represents the fraction of the 
total intracranial volume occupied by that structure.

cheers
Bruce
On Thu, 24 Oct 2013, 
Dorian P. wrote:

> Thank you Douglas.
> The eTIV has values like 1543825. Dividing ROIs by this value would create
> very small values.
> 
> Is there a standard TIV (i.e. from the talairach brain) to use as
> denominator for creating a ratio value? Or what is the best way to create a
> reasonable factor (i.e. 0.7-1.3) to correct/normalize roi volumes?
> 
> Dorian
> 
> 
> 
> 2013/10/24 Douglas N Greve <gr...@nmr.mgh.harvard.edu>
>
>       On 10/24/2013 10:37 AM, Dorian P. wrote:
>       > Dear all,
>       >
>       > Excuse if these are simple questions but I am a bit confused
>       on the
>       > significance of the volume measures.
>       >
>       > 1. Are the volumes of ROIs calculated after normalization?
> No, everything is done in native space.
> >
> > 2. If volumes are calculated post-normalization, why is correction
> for
> > eTIV needed?
> >
> > 3. What is the quickest way to correct for eTIV?
> Not sure what you mean by the "quickest". Usually the ROI volumes are
> divided by the eTIV or the eTIV is used as a regressor
> doug
> >
> > Thank you.
> > Dorian
> > TJU
> >
> >
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> 
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
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