Hi Sarah

what ROIs do you mean? And did you correct for the reduced surface area in fsaverage w.r.t. the individual surfaces? If not, it's not surprising that fsaverage ROIs have less surface area. It is an average surface and less folded than any individual.

cheers
Bruce


On Mon, 7 Oct 2013, Jensen, Sarah wrote:


Hi Freesurfer users,


I am analysing some volumetric data and have noticed that the volumes I
extract from my participants are very different from the volumes of my
templates in fsaverage space. I for instance have two ROIs that stand out as
big (about 6-8 times larger that the other ROIS) in fsaverage space, but
come out as almost indistinguishable from the other ROIs in my data. When I
sort my ROIs according to size there seems to be no consistency between the
size in fsaverage space and my subjects, and the correlation between the
volume in fsaverage and my subjects is about .05 - 0.1. 


I am new to freesurfer, and would intuitively expect greater consistency
between the ROIs in fsaverage and the subjects. Has anyone else had similar
experiences, and is this lack of consistency between volumes in fsaverage
space and participant data perfectly normal?


Thanks,


Sarah 


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