Sandra, what was your final command line?
doug

On 07/03/2013 06:28 AM, Sandra Preissler wrote:
> Dear Doug,
>
> Thanks a lot for your advice.
>
> We followed the examples on the wiki 
> (http://ftp.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis#AssembletheData.28mrispreproc.29)
>  
> and tried to analyze our data as described.
> We have a single group with two continuous covariates. Therefore we 
> created the freesurfer descriptor file (g1v2_I.fsgd) and three 
> contrast files (main.mtx; age.mtx; Amputationsdauer.mtx). The 
> preprocessing finished without error for both hemispheres.
>
> The following command line we used for the preprocessing:
> mris_preproc --fsgd qdec/GLM/g1v2_I.fsgd --cache-in 
> long.thickness-avg.fwhm10.fsaverage --target fsaverage --hemi lh --out 
> lh.g1v2_I.thickness.10.mgh
>
> After this we tried the mri_glmfit for our longitudinal data.
> Our command line was the following:
> mri_glmfit --glmdir g1v2_I --y lh.g1v2_I.thickness.10.mgh --fsgd 
> qdec/GLM/g1v2_I.fsgd --C qdec/GLM/main.mtx --C qdec/GLM/age.mtx --C 
> qdec/GLM/Amputationsdauer.mtx
>
> We get the error message:
> ERROR: you must use '--surface subject hemi' with surface data
>
> Therfore we tried to specify
>
> subject as fsaverage,
> hemi as lh,
> surface as thickness.
>
> Unfortunately, this did not work out and other alternative approaches 
> to solve this problem did not function as well.
>
> Do we have to create a subject descriptor file for our longitudinal 
> templates?
> Or did we miss anything else?
> We thought about creating the --X “design matrix file” for 
> longitudinal data, we found the instruction for between factors. But 
> this could not work for our data.
>
> Best regards
> Sandra
>
>
>
>
> -----Nachricht von gr...@nmr.mgh.harvard.edu -----Datum: Fri, 28 Jun 
> 2013 10:40:57 -0400
> Von: Douglas N Greve <gr...@nmr.mgh.harvard.edu>
> Betreff: Re: [Freesurfer] longitudinal analyses for one group
> An: freesurfer@nmr.mgh.harvard.edu
>
> Hi Sandra, you cannot do the longitudinal statistical analysis in QDEC.
> You will have to use mri_glmfit. Look at the FSGD examples on the wiki.
> doug
>
>
>
>
>
> On 06/28/2013 03:28 AM, Sandra Preissler wrote:
>
>
> [Zitattext verstecken]
> Dear freesurfer experts,
>
> we want to do longitudinal analyses for two different time points in
> only one group (We do not have a control group or different groups
> within the intervention). So we did the longitudinal processing as
> described in the tutorial
> (http://ftp.nmr.mgh.harvard.edu/fswiki/FsTutorial/LongitudinalTutorial#PreparingtheData-QCACHE).
>  
>
> Now we tried to investigate the results with Qdec. We wanted to test
> whether the averaged change of thickness between pre-test and
> post-test differs from zero. We had the experience that we could only
> test the averaged thickness by choosing a discrete factor in Qdec. Our
> Problem is that we don't have a control group. So we couldn't choose
> the group variable as discrete factor.
> It's an pre-post-design with only one group.
>
> Is it possible to investigate changes in thickness between pre-test
> and post-test without choosing a factor? Or do we have to create a
> group variable as discrete factor?
>
> Can you help us in fixing this problem?
>
> Thanks in advance!
>
> Sandra
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

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