I would do the subtraction first then do the STC.

On 04/01/2013 12:15 PM, Meryem Ayse Yucel wrote:
> Doug,
>
> I use preproc-sess 's -stc up option to time correct my slices. I only
> have 6 slices.
>
> Donald,
>
> I am not calculating absolute CBF values using the calibration scan. I
> pre-process the data and then either surround-subtract or just subtract
> tag from control to get CBF, would it still be a problem to use slice time
> correction?
>
>
> Thanks,
>
>
> Meryem
>
>
> Message: 11
> Date: Fri, 29 Mar 2013 13:40:42 -0400
> From: "MCLAREN, Donald" <mclaren.don...@gmail.com>
> Subject: Re: [Freesurfer] slice timing
> To: Douglas N Greve <gr...@nmr.mgh.harvard.edu>
> Cc: freesurfer@nmr.mgh.harvard.edu
> Message-ID:
>          <CAKwrF_XJfg=prtm2htz12fn74vtp2qgzqffagkezbjo+pxd...@mail.gmail.com>
> Content-Type: text/plain; charset="iso-8859-1"
>
> If you are using ASL, you do not want to use Slice timing. You must compute
> the CBF maps and keep the slice timing intact.
>
> Removing the time delay between slices will lead to the wrong CBF values as
> the CBF equations have the time delay in the equation.
>
> Best Regards, Donald McLaren
> =================
> D.G. McLaren, Ph.D.
> Research Fellow, Department of Neurology, Massachusetts General Hospital and
> Harvard Medical School
> Postdoctoral Research Fellow, GRECC, Bedford VA
> Website: http://www.martinos.org/~mclaren
> Office: (773) 406-2464
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> On Fri, Mar 29, 2013 at 1:08 PM, Douglas N Greve
> <gr...@nmr.mgh.harvard.edu>wrote:
>
>> what are you using to do STC? I think by default FSL will move it to the
>> middle slice, but there is probably a way to make take into account the
>> fact that the slices are not uniform over the TR. You should contact the
>> list of the software you are using to get a definative answer.
>> doug
>>
>>
>> On 03/29/2013 11:37 AM, Meryem Ayse Yucel wrote:
>>> Hi,
>>>
>>> I am running a pASL sequence with a TR = 3 sec and TI2 = 1.8. I am
>>> wondering when I do slice time correction does that move all slices to
>> the
>>> mid of TR that is 1.5 s prior in time or, it moves them to the timing of
>>> the mid slice, which would be the mid of image acquisition aorund 0.6 sec
>>> prior in time with respect to the end of TR.
>>>
>>> Thank you,
>>>
>>> Meryem
>>> _______________________________________________
>>> Freesurfer mailing list
>>> Freesurfer@nmr.mgh.harvard.edu
>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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