On 03/28/2013 03:53 PM, Tudor Popescu wrote:
> I was wondering if anybody is able to help with (any one of) these 
> questions? That would be really helpful, as I could not find an answer 
> on the wiki.
>
> Many thanks in advance!
>
> On 26 March 2013 20:44, Tudor Popescu <tud...@gmail.com 
> <mailto:tud...@gmail.com>> wrote:
>
>     Hi everyone,
>
>
>     My QDEC analysis ran into an error message that seems to be a
>     "classic" (and, so far, it seems unsolved), from mri_concat, which
>     I've described in a separate message, just sent.
>
>
>     I have, however, more theoretical questions about QDEC, which I
>     hope some kind soul will help me with:
>
>
>     - why does QDEC only provide the volume of /subcortical/
>     structures under StatsDataImport/aseg.volume, when the automatic
>     GM/WM segmentation is done for the entire brain, not just for
>     subcortical regions?
>
No reason in particular. You can add them into the qdec table.
>
>
>     - how are the volume measurements provided in aseg.volume
>     different from the ones done obtained with a VBM analysis?
>
Does VBM give segmentation volumes? I thought it was voxel-wise exploratory.
>
>     - why is /volume /the result of /segmentation /(aseg.volume)
>     whereas /thickness /derives from /parcelation
>     /(rh.aparc.thickness)? Is it not the case that both operations
>     (segmentation+parcellation) are necessary to calculate volume as
>     well as thickness?
>
You can get volume from parcellations too (this is supplied in the 
?h.apac.stats file). You can't get thickness from non-surface structures 
like amygdala.
>
>
>     - how is a QDEC thickness analysis different from a regular
>     AN(C)OVA in which you are interested in main and interaction
>     effects of the IVs on the DV? I ask this because some of the
>     questions that appear in QDEC's Analysis Results tab – e.g. "is
>     the correlation between (DV) and (IV) different from zero?" –
>     would not (I think) be directly answerable by an ANOVA 
>
Often times they are the same, depends on the contrast. I don't know 
what IV and DV are so I can't answer your specific question.
>
>     - would the same type of ANOVA done by QDEC be doable by
>     extracting the values of the DV for each subject (using e.g.
>     /aseg.volume/) and then doing the ANOVA in e.g. SPSS? If so, when
>     would you do one versus the other?
>
Yes. QDEC is an exploratory voxel-based method so effects don't have to 
lie cleanly within an ROI boundary.
>
>     - why is it that only continuous factors (e.g. age) can be taken
>     in the analysis as nuisance factors, when discrete variables (e.g.
>     gender) might also be irrelevant for a particular analysis and
>     thus belong to the Nuisance Factor list?
>
It is just a matter of convenience in making the contrasts. ie, it is 
easy to extend our contrast making code to add nuisance continuous variables
doug
>
>     Many thanks in advance!!
>
>     Tudor
>
>
>
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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