No, the subcortical calculation sums the number of voxels. For voxels on
the edge of a structure, there is a partial volume calculation based on
the intensity of the voxel and the mean intensities of the adjacent
structures.
doug




On 01/16/2013 05:52 PM, KimMJ wrote:
>
>
> ------------------------------------------------------------------------
> Dear Dr. Greve
>
> Thanks so much for your quick and clear response.
> One additional question here.
> Is this volume calculation method you have mentioned also applied to
> volume measurement of subcortical GM structure (in addition to
> cortical GM volume)?
>
> Thank you again
> Kim
>
>
>
> Date: Tue, 15 Jan 2013 23:16:04 -0500
> From: gr...@nmr.mgh.harvard.edu
> To: freesurfer@nmr.mgh.harvard.edu
> Subject: Re: [Freesurfer] A question regarding volume calculation
>
> Hi Kim, yes it is surface area times thickness. A volume at each
> vertex is computed as the average area of the triangles around the
> vertex times the thickness at that vertex. The volume of a
> parcellation is then the sum of the volumes of the vertices in that
> parcellation.
> doug
>
>
> On 1/15/13 9:03 PM, KimMJ wrote:
>
>     Dear experts
>
>
>     I'm currently preparing a paper using the results of automatic
>     volumetric segmentation of subcortical and cortical grey matter
>     structures from aseg.stats and aparc.stats files.
>     I have cited previous article by Desikan RS, et al (Neuroimage
>     2006;31:968-980) for the cortical GM volumetric segmentation, and
>     Fischl B, et al (Neuron 2002;33:341-355) for the subcortical GM
>     volumetric segmentation.
>     At this point, my question is how volumes of these structures
>     calculated. Is this volume of each GM structure based on surface
>     area multiplied by cortical thickness?
>
>     Apology for the newbie's question.
>     Thank you in advance for your help.
>
>     Kim MJ
>
>
>
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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