Hi Juergen, how are you judging whether a volume is flipped or not? The 
freesurfer tools should display properly regardless of the qfactor as 
long as the qform matrix is correct.
doug


On 01/11/2013 08:40 AM, Jürgen Hänggi wrote:
> NIFTI q-factor

Dear FS experts

Please can you confirm that the NIFTI q-factor in the NIFTI header has to be
negative (e.g. -1) in order to have correct right and left orientation.

When the NIFTI q-factor is positive in my T1-w. and DTI images, then the
left and the right hemisphere seem to be flipped.

Thanks in advance
Regards
Jürgen Hänggi

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