When we added the --spm-nii option, the problem disappears. The
following thread is also relevant:
https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2011-April/017981.html


On Tue, Dec 18, 2012 at 8:26 PM, MCLAREN, Donald
<mclaren.don...@gmail.com> wrote:
> Thanks, that's what I thought might be happening. I'll check a few
> different programs to see if I can recover the correct orientation. If
> we need to reverse the images, would you recommend doing it before or
> after the bbregister step? Would it be sufficient just to change the
> header of the image or do we need to physically change the data?
>
> Best Regards, Donald McLaren
> =================
> D.G. McLaren, Ph.D.
> Research Fellow, Department of Neurology, Massachusetts General Hospital and
> Harvard Medical School
> Postdoctoral Research Fellow, GRECC, Bedford VA
> Website: http://www.martinos.org/~mclaren
> Office: (773) 406-2464
> =====================
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>
> On Tue, Dec 18, 2012 at 11:20 PM, Douglas Greve
> <gr...@nmr.mgh.harvard.edu> wrote:
>> Hi Donald, it might be the case. If the fmri has an ordering such that the
>> columns increase as you go from left to right, then they will have to be
>> reversed when you map them to the orig.mgz. This is generally not a problem
>> because we always keep track of which side is left and right. If you are
>> using a visualization tool that does not read in and act on the geometry,
>> then things can appear to flip around.
>>
>> doug
>>
>>
>>
>> On 12/18/12 8:47 PM, MCLAREN, Donald wrote:
>>
>> Dear All,
>>
>> I've noticed something strange with some data I'm helping to process:
>>
>> When looking at the L/R asymmetry in the brains (attached), the images
>> seem to flip after bbregister/mri_vol2vol. The exact commands:
>> bbregister --s FS_D011 --mov meanfMRI.nii --reg register.dat --init-spm --t2
>> mri_vol2vol --s FS_D011 --targ orig.mgz --mov fMRI.nii --reg
>> register.dat --no-resample --o transformed_fMRI.nii
>>
>> I've attached a document that shows the flipping. You'll notice the
>> highest point of the ventricle flips sides after
>> bbregister/mri_vol2vol. Any thoughts on what is going on would be
>> appreciated.
>>
>> The contents of register.dat are as follows:
>> FS_D011
>> 3.000000
>> 3.540000
>> 0.150000
>> -9.972292184829712e-01 -6.125224381685257e-02 4.221317172050476e-02
>> 1.619825601577759e+00
>> 6.049362570047379e-02 -3.374822735786438e-01 9.393859505653381e-01
>> -1.230294322967529e+01
>> 4.329330846667290e-02 -9.393369555473328e-01 -3.402525186538696e-01
>> -1.072110843658447e+01
>> 0 0 0 1
>> round
>>
>>
>> Best Regards, Donald McLaren
>> =================
>> D.G. McLaren, Ph.D.
>> Research Fellow, Department of Neurology, Massachusetts General Hospital and
>> Harvard Medical School
>> Postdoctoral Research Fellow, GRECC, Bedford VA
>> Website: http://www.martinos.org/~mclaren
>> Office: (773) 406-2464
>> =====================
>> This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED
>> HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is
>> intended only for the use of the individual or entity named above. If the
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>> responsible for delivering it to the intended recipient, you are hereby
>> notified that you are in possession of confidential and privileged
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>> unintentionally, please immediately notify the sender via telephone at (773)
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>>
>>
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